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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Oceania Insignia Cruise Ship10 Night - Classic Canal & Tropics
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Willemstad AN, Oranjestad, Montego Bay, George Town, Miami
2026 Sails: Apr 4, More...
Queen Anne Cruises25 Night - Los Angeles to Southampton
Starting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Apr 5, More...
Queen Anne Cruises14 Night - Los Angeles to Miami
Starting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Apr 5, More...
Disney Magic Cruise Ship14 Night - Westbound Panama Canal Cruise from Galveston Ending in San Diego
Starting in Galveston, Cozumel, Mexico, Cartagena ES, Panama Canal, Puerto Vallarta, Cabo San Lucas, San Diego
2026 Sails: Apr 5, More...
HAL Eurodam Cruise Ship20 Night - Panama Canal with History Channel
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA, Seattle, Washington
2026 Sails: Apr 5, More...
HAL Eurodam Cruise Ship19 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA
2026 Sails: Apr 5, More...
HAL Eurodam Cruise Ship15 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Apr 5, More...
Grand Princess Cruise Ship27 Night - Panama Canal and Caribbean Adventurer
Starting in San Juan, Puerto Rico, St Thomas, US Virgin Islands, St Kitts, Aruba, Curacao, Bonaire, Caribbean Netherlands, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 5, More...
Star Seeker Cruises22 Night - Star Collector : Central American Explorations via the Panama Canal
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Curu, Costa Rica, Playas del Coco, Puerto Chiapas, Huatulco, Manzanillo, Puerto Vallarta
2026 Sails: Apr 6, More...
Star Seeker Cruises14 Night - Star Collector : Rainforest Refuges of Panama & Costa Rica via the Panama Canal
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Apr 6, More...


Panama Canal Cruises