Palermo Cruises
Cruises that visit Mediterranean: Italy: Palermo
Cruises that depart from Palermo
10 Night - Visions of Byzantium
Starting in Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...
8 Night - A Circumnavigation of Sicily - with Smithsonian Journeys
Starting in Valletta, Porto Empedocle, Sicily, Tunis, Trapani, Sicily, Palermo, Sicily, Lipari, Aeolian Islands, Sailing in front of Stromboli, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: Aug 29, 2027: May 10, More...
9 Night - Ramblas & the Rivieras
Starting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa / Tuscany (Livorno), Ajaccio (Corsica), Olbia / Porto Cervo (Sardinia), Palermo (Sicily), Valletta, Rome (Civitavecchia)
2026 Sails: Sep 5, More...
11 Night - Western Mediterranean from Athens (Pireo)
Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 9, More...13 Night - Western Mediterranean from Athens (Pireo)
Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 9, More...12 Night - Western Mediterranean from Athens (Pireo)
Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille
2026 Sails: Sep 9, More...
42 Night - Grand Europe Holiday
Starting in London (Tilbury), Ijmuiden, Edinburgh (Newhaven), Aberdeen, Lerwick (Shetland Islands), Portree (Isle of Skye), Belfast, Dublin (Dun Laoghaire), Paris (Le Havre), St Peter Port, Guernsey, Bordeaux, Bilbao, Gijon, Spain, La Coruna, Oporto, Lisbon, Seville (Cadiz), Malaga, Cartagena ES, Palma De Mallorca, Barcelona, Provence (Marseille), Cinque Terre (La Spezia), Ajaccio (Corsica), Cagliari (Sardinia), Palermo (Sicily), Naples / Pompeii, Rome (Civitavecchia), Sorrento / Capri, Messina (Sicily), Valletta, Crotone (Calabria), Corfu, Kotor, Dubrovnik, Croatia, Zadar, Koper, Venice (Fusina)
2026 Sails: Sep 11, More...10 Night - Western Mediterranean from Catania
Starting in Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 12, More...8 Night - Western Mediterranean from Catania
Starting in Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 12, More...9 Night - Western Mediterranean from Taranto
Starting in Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 13, More...
Cruises that visit Mediterranean: Italy: Palermo
Cruises that depart from Palermo
Click on a cruise ship itinerary that visits Palermo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Palermo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Visions of ByzantiumStarting in Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...
8 Night - A Circumnavigation of Sicily - with Smithsonian JourneysStarting in Valletta, Porto Empedocle, Sicily, Tunis, Trapani, Sicily, Palermo, Sicily, Lipari, Aeolian Islands, Sailing in front of Stromboli, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: Aug 29, 2027: May 10, More...
9 Night - Ramblas & the RivierasStarting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa / Tuscany (Livorno), Ajaccio (Corsica), Olbia / Porto Cervo (Sardinia), Palermo (Sicily), Valletta, Rome (Civitavecchia)
2026 Sails: Sep 5, More...
11 Night - Western Mediterranean from Athens (Pireo)Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 9, More...
13 Night - Western Mediterranean from Athens (Pireo)Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 9, More...
12 Night - Western Mediterranean from Athens (Pireo)Starting in Athens (Piraeus), Malta / La Valletta, Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille
2026 Sails: Sep 9, More...
42 Night - Grand Europe HolidayStarting in London (Tilbury), Ijmuiden, Edinburgh (Newhaven), Aberdeen, Lerwick (Shetland Islands), Portree (Isle of Skye), Belfast, Dublin (Dun Laoghaire), Paris (Le Havre), St Peter Port, Guernsey, Bordeaux, Bilbao, Gijon, Spain, La Coruna, Oporto, Lisbon, Seville (Cadiz), Malaga, Cartagena ES, Palma De Mallorca, Barcelona, Provence (Marseille), Cinque Terre (La Spezia), Ajaccio (Corsica), Cagliari (Sardinia), Palermo (Sicily), Naples / Pompeii, Rome (Civitavecchia), Sorrento / Capri, Messina (Sicily), Valletta, Crotone (Calabria), Corfu, Kotor, Dubrovnik, Croatia, Zadar, Koper, Venice (Fusina)
2026 Sails: Sep 11, More...
10 Night - Western Mediterranean from CataniaStarting in Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 12, More...
8 Night - Western Mediterranean from CataniaStarting in Catania, Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 12, More...
9 Night - Western Mediterranean from TarantoStarting in Taranto, Malta / La Valletta, La Goulette, Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona, Marseille, Barcelona
2026 Sails: Sep 13, More...
