Italy Cruises

Cruises that visit Mediterranean: Italy

Cruises that depart from Italy

See all River Cruises that visit Italy

Click on a cruise ship itinerary that visits Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Oceania Cruises, Oceania Marina

7 Night - Etruscan Waterways
Starting in Barcelona, Toulon, Portofino, Cinque Terre (La Spezia), Ajaccio (Corsica), Olbia / Porto Cervo (Sardinia), Naples / Pompeii, Rome (Civitavecchia)
2026 Sails: Apr 21, More...

Oceania Cruises, Oceania Nautica

10 Night - Charmed Rivieras
Starting in Barcelona, Palamos, Sete, Provence (Marseille), Toulon, Ajaccio (Corsica), Golfo Aranci, Portofino, Florence / Pisa / Tuscany (Livorno), Portoferraio (Elba), Rome (Civitavecchia)
2026 Sails: Apr 21, More...

Regent Seven Seas Cruises, Seven Seas Grandeur

14 Night - Journey to the Golden Horn
Starting in Barcelona, Cruising the Strait of Messina, Messina (Sicily), Cruising the Mediterranean Sea, Alexandria EG, Cruising the Mediterranean Sea, Heraklion (Crete), Santorini, Athens (Piraeus), Mykonos, Istanbul
2026 Sails: Apr 21, More...

Costa Cruise Lines, Costa Favolosa

11 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Savona, Marseille, Cartagena ES, Spain, Malaga, Gibraltar, Cadice, Lisbon, Barcelona
2026 Sails: Apr 22, More...

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Valencia
Starting in Valencia, La Spezia, Civitavecchia, Savona, Marseille, Palma De Mallorca, Valencia
2026 Sails: Apr 22, More...

Holland America Line (HAL), HAL Oosterdam

Deal link -> Special

11 Night - Mediterranean Splendor : Amalfi Coast & Ancient Ruins
Starting in Barcelona, Spain, Villefranche-sur-Mer (Nice), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii / Amalfi), Italy, Taormina, Italy, Souda (Chania), Greece, Rhodes, Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece
2026 Sails: Apr 22, More...

MSC Cruises, MSC Fantasia

5 Night - Mediterranean
Starting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Naples (Pompeii), Italy, Barcelona, Spain
2026 Sails: Apr 22, More...

MSC Cruises, MSC Musica

7 Night - Mediterranean
Starting in Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2026 Sails: Apr 22, Apr 29, May 6, May 13, May 20, May 27, Jun 3, Jun 10, Jun 17, Jun 24, Jul 1, Jul 8, Jul 15, Jul 22, Jul 29, Aug 5, Aug 12, Aug 19, Aug 26, Sep 2, Oct 7, More...

MSC Cruises, MSC Splendida

7 Night - Mediterranean
Starting in Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy, Palermo (Monreale), Italy
2026 Sails: Apr 22, More...

MSC Cruises, MSC World Europa

7 Night - Mediterranean
Starting in La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta
2026 Sails: Apr 22, Apr 29, May 6, May 13, May 20, May 27, Jun 3, Jun 10, Jun 17, Jun 24, Jul 1, Jul 8, Jul 15, Jul 22, Jul 29, Aug 5, Aug 12, Aug 19, Aug 26, Sep 2, Sep 9, Sep 16, Sep 23, Sep 30, More...

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