Sicily Cruises
Cruises that visit Mediterranean: Italy: Sicily
14 Night - Mediterranean Antiquities
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Jan 4, More...
14 Night - Mediterranean Antiquities
Starting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Jan 5, More...
10 Night - Civitavecchia to Barcelona
Starting in Civitavecchia (Rome), Naples, Palermo, Sicily, Valletta, Tunis (La Goulette), Cagliari (Sardinia), Valencia, Barcelona
2026 Sails: Jan 14, More...10 Night - Barcelona to Civitavecchia
Starting in Barcelona, Valencia, Cagliari (Sardinia), Valletta, Tunis (La Goulette), Palermo, Sicily, Naples, Civitavecchia (Rome)
2026 Sails: Jan 24, More...
13 Night - Greece, Italy & Turkey Cruise
Starting in Barcelona, Spain, Sicily (Messina), Italy, Valletta, Malta, Heraklion (Iraklion), Crete, Rhodes, Greece, Ephesus (Kusadasi), Turkey, Thessaloniki, Greece, Nafplio, Greece, Athens (Piraeus), Greece
2026 Sails: Feb 3, More...14 Night - Mediterranean Antiquities
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Feb 3, More...
7 Night - Journey to Antiquities
Starting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Feb 5, More...14 Night - Mediterranean Antiquities
Starting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Feb 5, More...7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Feb 10, Apr 4, More...10 Night - Fusina to Civitavecchia
Starting in Fusina (Venice), Zadar, Siracusa (Sicily), Livorno (Tuscany), Villefranche, Genoa, Civitavecchia (Rome)
2026 Sails: Feb 13, More...
Cruises that visit Mediterranean: Italy: Sicily
Click on a cruise ship itinerary that visits Sicily (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Sicily), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Mediterranean AntiquitiesStarting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Jan 4, More...
14 Night - Mediterranean AntiquitiesStarting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Jan 5, More...
10 Night - Civitavecchia to BarcelonaStarting in Civitavecchia (Rome), Naples, Palermo, Sicily, Valletta, Tunis (La Goulette), Cagliari (Sardinia), Valencia, Barcelona
2026 Sails: Jan 14, More...
10 Night - Barcelona to CivitavecchiaStarting in Barcelona, Valencia, Cagliari (Sardinia), Valletta, Tunis (La Goulette), Palermo, Sicily, Naples, Civitavecchia (Rome)
2026 Sails: Jan 24, More...
13 Night - Greece, Italy & Turkey CruiseStarting in Barcelona, Spain, Sicily (Messina), Italy, Valletta, Malta, Heraklion (Iraklion), Crete, Rhodes, Greece, Ephesus (Kusadasi), Turkey, Thessaloniki, Greece, Nafplio, Greece, Athens (Piraeus), Greece
2026 Sails: Feb 3, More...
14 Night - Mediterranean AntiquitiesStarting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Feb 3, More...
7 Night - Journey to AntiquitiesStarting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Feb 5, More...
14 Night - Mediterranean AntiquitiesStarting in Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Feb 5, More...
7 Night - Journey to AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Feb 10, Apr 4, More...
10 Night - Fusina to CivitavecchiaStarting in Fusina (Venice), Zadar, Siracusa (Sicily), Livorno (Tuscany), Villefranche, Genoa, Civitavecchia (Rome)
2026 Sails: Feb 13, More...
