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Grand Cayman Island Cruises

Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island

Click on a cruise ship itinerary that visits Grand Cayman Island (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Grand Cayman Island), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Celebrity Cruises, Celebrity Silhouette
Celebrity Silhouette6 Night - Grand Cayman, Mexico & Key West
Starting in Fort Lauderdale, Florida, Key West, Florida, George Town, Grand Cayman, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Apr 12, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel7 Night - Bahamas, Mexico & Cayman Cruise
Starting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Apr 12, More...
Royal Caribbean, Independence of the Seas
Independence of the Seas7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Falmouth, Jamaica, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2026 Sails: Apr 12, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit17 Night - Panama Canal Westward Cruise
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 13, More...
Disney Cruise Line, Disney Treasure
Disney Treasure7 Night - Western Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Castaway Cay, Port Canaveral
2026 Sails: Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, 2027: Apr 3, Apr 17, May 1, May 15, May 29, More...
Celebrity Cruises, Celebrity Eclipse
Celebrity Eclipse6 Night - Grand Cayman, Mexico & Perfect Day
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Apr 19, More...
Royal Caribbean, Radiance of the Seas
Radiance of the Seas8 Night - Western Caribbean Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Cozumel, Mexico, Roatan, Honduras, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Apr 22, More...
Carnival Cruise Lines, Carnival Sunrise
Carnival Sunrise5 Night - Western Caribbean
Starting in Miami, Fl, Celebration Key, the Bahamas, Grand Cayman, Cayman Islands, Miami, Fl
2026 Sails: Apr 27, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2026 Sails: May 2, More...
Carnival Cruise Lines, Carnival Horizon
Carnival Horizon6 Night - Western Caribbean
Starting in Miami, Fl, Celebration Key, the Bahamas, Montego Bay, Jamaica, Grand Cayman, Cayman Islands, Miami, Fl
2026 Sails: May 3, Jun 28, Jul 12, Jul 26, Aug 23, Sep 6, Sep 20, Oct 18, Nov 1, Nov 15, 2027: Jan 4, Jan 10, Feb 7, Feb 21, Mar 7, Apr 4, Apr 18, More...

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Grand Cayman Island Cruises