Grand Cayman Island Cruises
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
6 Night - Grand Cayman, Bahamas & Mexico
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 11, Feb 22, Mar 8, Apr 5, More...
14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 11, Feb 8, More...
8 Night - Caribbean & Panama
Starting in Tampa, Fl, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Cayman, Cayman Islands, Tampa, Fl
2026 Sails: Jan 17, Mar 14, More...
6 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, George Town, Grand Cayman, Falmouth, Jamaica, Grand Bahama Island, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 17, More...
6 Night - Grand Cayman, Mexico & Key West
Starting in Fort Lauderdale, Florida, Key West, Florida, George Town, Grand Cayman, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Apr 12, More...
7 Night - Bahamas, Mexico & Cayman Cruise
Starting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...7 Night - Western Caribbean with Grand Cayman
Starting in Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, More...14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, More...
7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Falmouth, Jamaica, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
10 Night - Western Caribbean
Starting in Galveston, Tx, Cozumel, Mexico, Belize, Mahogany Bay, Roatan, Montego Bay, Jamaica, Grand Cayman, Cayman Islands, Galveston, Tx
2026 Sails: Jan 19, Apr 13, More...
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
Click on a cruise ship itinerary that visits Grand Cayman Island (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Grand Cayman Island), please visit: Cruise Search or try our Virtual Cruise Advisor™.
6 Night - Grand Cayman, Bahamas & MexicoStarting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 11, Feb 22, Mar 8, Apr 5, More...
14 Night - Eastern / Western Caribbean AdventurerStarting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 11, Feb 8, More...
8 Night - Caribbean & PanamaStarting in Tampa, Fl, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Cayman, Cayman Islands, Tampa, Fl
2026 Sails: Jan 17, Mar 14, More...
6 Night - Western Caribbean CruiseStarting in Orlando (Port Canaveral), Fl, George Town, Grand Cayman, Falmouth, Jamaica, Grand Bahama Island, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 17, More...
6 Night - Grand Cayman, Mexico & Key WestStarting in Fort Lauderdale, Florida, Key West, Florida, George Town, Grand Cayman, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Apr 12, More...
7 Night - Bahamas, Mexico & Cayman CruiseStarting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
7 Night - Western Caribbean with Grand CaymanStarting in Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, More...
14 Night - Eastern / Western Caribbean AdventurerStarting in Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, More...
7 Night - Western Caribbean & Perfect DayStarting in Miami, Florida, Perfect Day Cococay, Bahamas, Falmouth, Jamaica, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
10 Night - Western CaribbeanStarting in Galveston, Tx, Cozumel, Mexico, Belize, Mahogany Bay, Roatan, Montego Bay, Jamaica, Grand Cayman, Cayman Islands, Galveston, Tx
2026 Sails: Jan 19, Apr 13, More...
