Grand Cayman Island Cruises
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
7 Night - Western Caribbean with Grand Cayman
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...14 Night - Eastern / Western Caribbean Adventurer Holiday
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...
7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2025 Sails: Dec 7, More...
5 Night - Western Caribbean
Starting in Miami, Fl, Ocho Rios, Jamaica, Grand Cayman, Cayman Islands, Miami, Fl
2025 Sails: Dec 8, 2026: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Jun 8, More...
5 Night - Western Caribbean Cruise
Starting in Miami, Florida, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2025 Sails: Dec 8, 2026: Jan 5, More...
7 Night - Western Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Castaway Cay, Port Canaveral
2025 Sails: Dec 13, Dec 27, 2026: Jan 10, Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 17, Oct 31, Nov 14, More...
8 Night - Western Caribbean Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Cozumel, Mexico, Roatan, Honduras, Puerto Costa Maya, Mexico, Tampa, Florida
2025 Sails: Dec 13, More...
6 Night - Western Caribbean
Starting in Miami, Fl, Cozumel, Mexico, Grand Cayman, Cayman Islands, Ocho Rios, Jamaica, Miami, Fl
2025 Sails: Dec 14, More...
6 Night - Grand Cayman, Bahamas & Mexico
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Nassau, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 14, Dec 28, 2026: Jan 11, Feb 22, Mar 8, Apr 5, Apr 19, More...14 Night - Eastern / Western Caribbean Adventurer Holiday
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Roatan (Mahogany Bay, Honduras), Cozumel, Mexico, Fort Lauderdale, Florida
2025 Sails: Dec 14, More...
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
Click on a cruise ship itinerary that visits Grand Cayman Island (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Grand Cayman Island), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Western Caribbean with Grand CaymanStarting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...
14 Night - Eastern / Western Caribbean Adventurer HolidayStarting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...
7 Night - Western Caribbean & Perfect DayStarting in Miami, Florida, Perfect Day Cococay, Bahamas, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2025 Sails: Dec 7, More...
5 Night - Western CaribbeanStarting in Miami, Fl, Ocho Rios, Jamaica, Grand Cayman, Cayman Islands, Miami, Fl
2025 Sails: Dec 8, 2026: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Jun 8, More...
5 Night - Western Caribbean CruiseStarting in Miami, Florida, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2025 Sails: Dec 8, 2026: Jan 5, More...
Deal link -> Special
7 Night - Western Caribbean Cruise from Port CanaveralStarting in Port Canaveral, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Castaway Cay, Port Canaveral
2025 Sails: Dec 13, Dec 27, 2026: Jan 10, Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 17, Oct 31, Nov 14, More...
8 Night - Western Caribbean CruiseStarting in Tampa, Florida, George Town, Grand Cayman, Cozumel, Mexico, Roatan, Honduras, Puerto Costa Maya, Mexico, Tampa, Florida
2025 Sails: Dec 13, More...
6 Night - Western CaribbeanStarting in Miami, Fl, Cozumel, Mexico, Grand Cayman, Cayman Islands, Ocho Rios, Jamaica, Miami, Fl
2025 Sails: Dec 14, More...
6 Night - Grand Cayman, Bahamas & MexicoStarting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Nassau, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 14, Dec 28, 2026: Jan 11, Feb 22, Mar 8, Apr 5, Apr 19, More...
14 Night - Eastern / Western Caribbean Adventurer HolidayStarting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Roatan (Mahogany Bay, Honduras), Cozumel, Mexico, Fort Lauderdale, Florida
2025 Sails: Dec 14, More...
