Cusco Cruises
Cruises that visit South America: Peru: Cusco
See all River Cruises that visit Cusco
15 Night - Peruvian Amazon & Machu Picchu Exploration
Starting in Lima, Lima, Fly to Iquitos (Nauta), Embark, Ucayali River, Clavero Lake, Yarapa River, Amazon River, Tahuayo River, San Pedro Forest, Nauta, Maranon River, Yanayacu-Pucate River, Amazon River, Samiria River, Ucayali River, Puerto Prado Forest, Amazon River, Nauta (Iquitos), Disembark, Fly to Cusco, Urubamba (the Sacred Valley), Urubamba (the Sacred Valley), Urubamba, Ollantaytambo, Aguas Calientes (Machu Picchu), Aguas Calientes (Machu Picchu), Cusco, Cusco, Cusco, Fly to Lima, Lima
2026 Sails: Apr 15, Jun 10, Dec 2, 2027: Jan 20, Mar 3, Apr 7, May 12, Jun 2, Jun 30, Aug 4, Sep 1, Sep 22, Oct 13, Nov 3, Dec 1, More...
12 Night - From the Inca Empire to the Peruvian Amazon with the Nazca Lines
Starting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2026 Sails: Jun 12, Jul 24, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, Nov 6, More...10 Night - From the Inca Empire to the Peruvian Amazon
Starting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2026 Sails: Jun 14, Jul 26, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 8, More...19 Night - From the Inca Empire to the Peruvian Amazon with the Nazca Lines & Galapagos Cruise
Starting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima / Quito, Quito, Baltra, Galapagos Islands (Embarkation) Santa Cruz Island, Santa Cruz Island, Floreana Island, Espanola Island, Galapagos Islands (Disembarkation) San Cristobal / Quito, Quito
2026 Sails: Oct 9, Oct 23, Nov 6, More...17 Night - From the Inca Empire to the Peruvian Amazon with Galapagos Cruise
Starting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima / Quito, Quito, Baltra, Galapagos Islands (Embarkation) Santa Cruz Island, Santa Cruz Island, Floreana Island, Espanola Island, Galapagos Islands (Disembarkation) San Cristobal / Quito, Quito
2026 Sails: Oct 11, Oct 25, Nov 8, More...
25 Night - Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey
Starting in Lima, Lima / Amazon, Amazon, Amazon / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cuzco, Cuzco, Cuzco / Santiago, Santiago / Valparaiso, Niebla, Chile, Puerto Montt, Chile, Castro, Isla Chiloe, Puerto Eden / Pio XI Glacier (Inner Fjords), Cruising Strait of Magellan, Punta Arenas, Chile, Chilean Fjords, Cape Horn, Ushuaia / Buenos Aires
2026 Sails: Oct 22, More...12 Night - From the Inca Empire to the Peruvian Amazon with the Nazca Lines
Starting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2027 Sails: Jan 1, Jan 29, Apr 9, Apr 30, May 7, May 21, Jun 4, Jun 11, Jul 23, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...10 Night - From the Inca Empire to the Peruvian Amazon
Starting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2027 Sails: Jan 3, Jan 31, Apr 11, May 2, May 9, May 23, Jun 6, Jun 13, Jul 25, Oct 3, Oct 10, Oct 17, Oct 24, Oct 31, Nov 7, More...
15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2027 Sails: Apr 2, Apr 9, Apr 16, Apr 23, Apr 30, May 7, May 14, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, Jul 2, Jul 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, More...
11 Night - Peru and Galapagos Escape
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Guayaquil, Ecuador, Guayaquil / Baltra / Embark Ship, Baltra / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2027 Sails: Apr 8, Apr 22, May 6, May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, Oct 21, Nov 18, Dec 2, Dec 16, Dec 30, 2028: Jan 13, Jan 27, Feb 10, Feb 24, Mar 9, More...
Cruises that visit South America: Peru: Cusco
See all River Cruises that visit Cusco
Click on a cruise ship itinerary that visits Cusco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cusco), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Peruvian Amazon & Machu Picchu ExplorationStarting in Lima, Lima, Fly to Iquitos (Nauta), Embark, Ucayali River, Clavero Lake, Yarapa River, Amazon River, Tahuayo River, San Pedro Forest, Nauta, Maranon River, Yanayacu-Pucate River, Amazon River, Samiria River, Ucayali River, Puerto Prado Forest, Amazon River, Nauta (Iquitos), Disembark, Fly to Cusco, Urubamba (the Sacred Valley), Urubamba (the Sacred Valley), Urubamba, Ollantaytambo, Aguas Calientes (Machu Picchu), Aguas Calientes (Machu Picchu), Cusco, Cusco, Cusco, Fly to Lima, Lima
2026 Sails: Apr 15, Jun 10, Dec 2, 2027: Jan 20, Mar 3, Apr 7, May 12, Jun 2, Jun 30, Aug 4, Sep 1, Sep 22, Oct 13, Nov 3, Dec 1, More...
12 Night - From the Inca Empire to the Peruvian Amazon with the Nazca LinesStarting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2026 Sails: Jun 12, Jul 24, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, Nov 6, More...
10 Night - From the Inca Empire to the Peruvian AmazonStarting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2026 Sails: Jun 14, Jul 26, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 8, More...
19 Night - From the Inca Empire to the Peruvian Amazon with the Nazca Lines & Galapagos CruiseStarting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima / Quito, Quito, Baltra, Galapagos Islands (Embarkation) Santa Cruz Island, Santa Cruz Island, Floreana Island, Espanola Island, Galapagos Islands (Disembarkation) San Cristobal / Quito, Quito
2026 Sails: Oct 9, Oct 23, Nov 6, More...
17 Night - From the Inca Empire to the Peruvian Amazon with Galapagos CruiseStarting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima / Quito, Quito, Baltra, Galapagos Islands (Embarkation) Santa Cruz Island, Santa Cruz Island, Floreana Island, Espanola Island, Galapagos Islands (Disembarkation) San Cristobal / Quito, Quito
2026 Sails: Oct 11, Oct 25, Nov 8, More...
25 Night - Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land JourneyStarting in Lima, Lima / Amazon, Amazon, Amazon / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cuzco, Cuzco, Cuzco / Santiago, Santiago / Valparaiso, Niebla, Chile, Puerto Montt, Chile, Castro, Isla Chiloe, Puerto Eden / Pio XI Glacier (Inner Fjords), Cruising Strait of Magellan, Punta Arenas, Chile, Chilean Fjords, Cape Horn, Ushuaia / Buenos Aires
2026 Sails: Oct 22, More...
12 Night - From the Inca Empire to the Peruvian Amazon with the Nazca LinesStarting in Arrive in Lima, Peru, Lima / Pisco / Paracas and Nazca Lines, Paracas / Ballestas Islands Cruise / Lima, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2027 Sails: Jan 1, Jan 29, Apr 9, Apr 30, May 7, May 21, Jun 4, Jun 11, Jul 23, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...
10 Night - From the Inca Empire to the Peruvian AmazonStarting in Lima, Peru, Lima, Sacred Valley, Machu Picchu, Cusco, Cusco / Lima / Iquitos / Nauta (Embarkation), Peruvian Amazon, Iquitos (Disembarkation), Lima
2027 Sails: Jan 3, Jan 31, Apr 11, May 2, May 9, May 23, Jun 6, Jun 13, Jul 25, Oct 3, Oct 10, Oct 17, Oct 24, Oct 31, Nov 7, More...
15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the IncaStarting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2027 Sails: Apr 2, Apr 9, Apr 16, Apr 23, Apr 30, May 7, May 14, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, Jul 2, Jul 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, More...
11 Night - Peru and Galapagos EscapeStarting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Guayaquil, Ecuador, Guayaquil / Baltra / Embark Ship, Baltra / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2027 Sails: Apr 8, Apr 22, May 6, May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, Oct 21, Nov 18, Dec 2, Dec 16, Dec 30, 2028: Jan 13, Jan 27, Feb 10, Feb 24, Mar 9, More...
