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Cusco Cruises

Cruises that visit South America: Peru: Cusco

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Click on a cruise ship itinerary that visits Cusco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cusco), please visit: Cruise Search or try our Virtual Cruise Advisor™.


National Geographic Islander II Tours11 Night - Peru and Galapagos Escape
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Guayaquil, Ecuador, Guayaquil / Baltra / Embark Ship, Baltra / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2026 Sails: Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 31, 2027: Jan 14, Jan 28, Feb 11, More...
National Geographic Delfina Tours15 Night - Galapagos by Catamaran, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 16, More...
National Geographic Endeavour II Tours15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Sep 25, Oct 2, More...
National Geographic Gemini Tours15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, More...
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Apr 23, May 21, Jun 4, Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Iquitos / Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima
2026 Sails: Apr 27, Jun 8, Jul 27, Aug 24, Sep 14, More...
Celebrity Flora Tours16 Night - Galapagos Outer Loop & Machu Picchu
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Gardner Bay (Espanola), Punta Suarez, Cormorant Point (Floreana), Post Office Bay, Floreana Island, Moreno Point, Isabela Island, Urbina Bay, Espinoza Point, Vicente Roca Point, South Plaza (Santa Cruz Island), Daphne Major / Cruising, Dragon Hill (Santa Cruz Island), Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2026 Sails: May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, Nov 27, Dec 11, Dec 25, 2027: Jan 8, Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...
Celebrity Flora Tours16 Night - Galapagos Inner Loop & Machu Picchu
Starting in Quito, Ecuador, Quito to Baltra Embarkation, Baltra Island (Galapagos), Egas Port, Santiago Island, Rabida Island, Elizabeth Bay, Tagus Cove, Isabela Island, Sullivan Bay (Santiago Island), Bartolome Island, Las Bachas, Santa Cruz Island, Daphne Major / Cruising, North Seymour Island, Puerto Baquerizo Moreno, San Cristobal Island, Punta Pitt, San Cristobal Island, Puerto Ayora, Santa Cruz Island, Baltra Island (Galapagos), Baltra / Quito Disembarkation Fly to Quito, Lima, Peru, Fly from Lima to Cuzco and the Sacred Valley, Peru, The Sacred Valley, Sacred Valley and Machu Picchu, Cuzco, Peru, Fly to Lima, Peru / Depart Lima, Peru, Depart Lima, Peru
2026 Sails: Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, Nov 6, Dec 4, Dec 18, 2027: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 26, Apr 9, Apr 23, May 7, May 21, More...
MS Santa Cruz II Tours13 Night - Galapagos Islands - in Darwin's Footsteps Plus Machu Picchu
Starting in Lima / Jorge Chavez International Airport, Cusco, Quito, Mosquera, Quito, Capitania Seymour, Baltra, Punta Pitt, San Cristobal, Mosquera, Puerto Baquerizo Moreno, Plazas Sur, Punta Pitt, San Cristobal, Santa Fe, Puerto Ayora, Plazas Sur, Puerto Ayora, Punta Suarez, Bahia Gardner, Islote Eden, Seymour Norte, Capitania Seymour, Baltra, Quito
2026 Sails: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, Nov 27, Dec 11, More...
MS Santa Cruz II Tours15 Night - Galapagos Islands - Nine of the Best Isles Plus Machu Picchu
Starting in Lima / Jorge Chavez International Airport, Cusco, Quito, Capitania Seymour, Baltra, Dragon Hill, Puerto Ayora, Punta Vicente Roca, Fernandina, Puerto Ayora, Post Office Bay, Champion Islet, Punta Cormorant, Las Bachas, Capitania Seymour, Baltra, Puerto Egas, Las Bachas, Buccaneer Cove, Bartolome, Puerto Egas, Rabida, Bartolome, Prince Philip Steps, Genovesa, Capitania Seymour, Baltra, Quito, Darwin Bay, Genovesa, Itabaca Channel
2026 Sails: Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, More...


Cusco Cruises