Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
27 Night - Panama Canal & Historic Sea of Cortez
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...15 Night - Panama Canal with History Channel
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...
5 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Feb 7, More...15 Night - Panama Canal-Panama City
Starting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Miami, Fl
2026 Sails: Feb 12, More...27 Night - Historic Sea of Cortez & Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...12 Night - Historical Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Feb 15, More...
6 Night - Cabo & Ensenada Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
14 Night - Inca & Aztec Kingdoms
Starting in Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Feb 21, More...17 Night - Repo - Panama Canal
Starting in Callao / Lima, Peru, Salaverry / Trujillo, Peru, Manta, Ecuador, Panama City, Panama, Puntarenas / Puerto Caldera, Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Acapulco, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Mar 11, More...
5 Night - Mexican Riviera
Starting in Long Beach (Los Angeles), Ca, Cabo San Lucas, Mexico, Ensenada, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Mar 21, Mar 30, Apr 18, May 14, May 19, May 28, Jun 2, Jun 11, Jun 16, Jun 25, Jul 9, Jul 14, Jul 23, Jul 28, Aug 6, Aug 11, Aug 20, Aug 25, Sep 3, Oct 29, 2027: Apr 1, Apr 6, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
27 Night - Panama Canal & Historic Sea of CortezStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...
15 Night - Panama Canal with History ChannelStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...
5 Night - Mexican Riviera - San DiegoStarting in San Diego, Ca, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Feb 7, More...
15 Night - Panama Canal-Panama CityStarting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Miami, Fl
2026 Sails: Feb 12, More...
27 Night - Historic Sea of Cortez & Panama CanalStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...
12 Night - Historical Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Feb 15, More...
6 Night - Cabo & Ensenada CruiseStarting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
14 Night - Inca & Aztec KingdomsStarting in Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Feb 21, More...
17 Night - Repo - Panama CanalStarting in Callao / Lima, Peru, Salaverry / Trujillo, Peru, Manta, Ecuador, Panama City, Panama, Puntarenas / Puerto Caldera, Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Acapulco, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Mar 11, More...
5 Night - Mexican RivieraStarting in Long Beach (Los Angeles), Ca, Cabo San Lucas, Mexico, Ensenada, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Mar 21, Mar 30, Apr 18, May 14, May 19, May 28, Jun 2, Jun 11, Jun 16, Jun 25, Jul 9, Jul 14, Jul 23, Jul 28, Aug 6, Aug 11, Aug 20, Aug 25, Sep 3, Oct 29, 2027: Apr 1, Apr 6, More...
