Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
16 Night - Panama Canal & Pacific Wonders
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Panama, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 21, More...
14 Night - Baja Peninsula, Wine Country and Pnw
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Avalon, California, San Francisco, California, Astoria, Oregon, Victoria CA, Canada, Vancouver, BC, CA
2026 Sails: Mar 28, More...
7 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Mazatlan, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Mar 28, More...
7 Night - Mexican Riviera
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 28, More...
27 Night - Eastern Caribbean Explorer & Panama Canal
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA, Seattle, Washington
2026 Sails: Mar 29, More...
26 Night - Eastern Caribbean Explorer & Panama Canal
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA
2026 Sails: Mar 29, More...
22 Night - Eastern Caribbean Explorer & Panama Canal
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Mar 29, More...
42 Night - Miami to Seattle
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 2, More...
32 Night - Miami to Seattle
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 2, More...
7 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Apr 4, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
16 Night - Panama Canal & Pacific WondersStarting in Miami, Florida, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Panama, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 21, More...
14 Night - Baja Peninsula, Wine Country and PnwStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Avalon, California, San Francisco, California, Astoria, Oregon, Victoria CA, Canada, Vancouver, BC, CA
2026 Sails: Mar 28, More...
7 Night - Mexican Riviera - San DiegoStarting in San Diego, Ca, Mazatlan, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Mar 28, More...
7 Night - Mexican RivieraStarting in Los Angeles, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 28, More...
27 Night - Eastern Caribbean Explorer & Panama CanalStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA, Seattle, Washington
2026 Sails: Mar 29, More...
26 Night - Eastern Caribbean Explorer & Panama CanalStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Avalon, California, Vancouver, BC, CA
2026 Sails: Mar 29, More...
22 Night - Eastern Caribbean Explorer & Panama CanalStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Mar 29, More...
42 Night - Miami to SeattleStarting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 2, More...
32 Night - Miami to SeattleStarting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 2, More...
7 Night - Mexican Riviera - San DiegoStarting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Apr 4, More...