Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
16 Night - Stars & Salsa
Starting in Los Angeles, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Panama Canal Transit, Cartagena CO, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2026 Sails: Jan 25, More...
7 Night - Ensenada, Cabo & Vallarta Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jan 26, More...
27 Night - Panama Canal & Historic Sea of Cortez
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...15 Night - Panama Canal with History Channel
Starting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...
5 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Feb 7, More...15 Night - Panama Canal-Panama City
Starting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Miami, Fl
2026 Sails: Feb 12, More...27 Night - Historic Sea of Cortez & Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...12 Night - Historical Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Feb 15, More...6 Night - Cabo & Ensenada Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
14 Night - Inca & Aztec Kingdoms
Starting in Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Feb 21, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
16 Night - Stars & SalsaStarting in Los Angeles, Cruising the Pacific Ocean, Cabo San Lucas, Cruising the Pacific Ocean, Acapulco, Cruising the Pacific Ocean, Puerto Quetzal, Cruising the Pacific Ocean, Puntarenas, Cruising the Pacific Ocean, Panama Canal Transit, Cartagena CO, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2026 Sails: Jan 25, More...
7 Night - Ensenada, Cabo & Vallarta CruiseStarting in Los Angeles, California, Ensenada, Mexico, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jan 26, More...
27 Night - Panama Canal & Historic Sea of CortezStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 31, More...
15 Night - Panama Canal with History ChannelStarting in Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 31, More...
5 Night - Mexican Riviera - San DiegoStarting in San Diego, Ca, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Feb 7, More...
15 Night - Panama Canal-Panama CityStarting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Miami, Fl
2026 Sails: Feb 12, More...
27 Night - Historic Sea of Cortez & Panama CanalStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 15, More...
12 Night - Historical Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Feb 15, More...
6 Night - Cabo & Ensenada CruiseStarting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
14 Night - Inca & Aztec KingdomsStarting in Lima / Machu Picchu (Callao), Salaverry, Manta, Puntarenas, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Feb 21, More...
