South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

South America
Shore Excursions

Lindblad Expeditions, National Geographic Resolution

16 Night - Exploring Patagonia's National Parks
Starting in Santiago, Chile, Puerto Natales / Embark Ship, Puerto Natales / Torres del Paine National Park, Tierra del Fuego / Karukinka Natural Park, Chilean Fjords, Inland Passage, Aysen / Coyhaique / Andes Mountains, Tantauco Park, Castro (Chiloe Island), Pumalin Douglas Tompkins National Park, Puerto Montt / Disembark Ship / Santiago
2027 Sails: Mar 5, More...

Lindblad Expeditions Tours, National Geographic Resolution Tours

Oceania Cruises, Oceania Marina

20 Night - Panama Canal Navigator
Starting in Miami, Cozumel, Mexico, Costa Maya, Mexico, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal Daylight Transit, Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Falmouth, George Town, Miami
2027 Sails: Mar 5, More...

Quark Expeditions Tours, World Voyager Quark Tours

10 Night - Antarctic Marine Mammals : the World of Whales and Seals
Starting in Arrive in Buenos Aires, Argentina, Fly to Ushuaia and Embark, At Sea / Drake Passage, Southbound, At Sea / Sailing toward Antarctica, Antarctic Peninsula, South Shetlands, At Sea / Drake Passage, Northbound, Disembark in Ushuaia and Fly to Buenos Aires
2027 Sails: Mar 5, More...

Silversea, Silver Nova

18 Night - Valparaiso to Miami
Starting in Valparaiso, Arica, Lima (Callao), Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cozumel, Quintana Roo, Miami, Fl
2027 Sails: Mar 5, More...

Costa Cruise Lines, Costa Diadema

7 Night - South America Roundtrip from Itajai
Starting in Itajai, Brazil, Santos / Sao Paulo, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil
2027 Sails: Mar 6, Mar 13, More...

Costa Cruise Lines, Costa Diadema

7 Night - South America Roundtrip from Santos
Starting in Santos / Sao Paulo, Buenos Aires, Argentina, Montevideo, Uruguay, Itajai, Brazil, Santos / Sao Paulo
2027 Sails: Mar 7, Mar 14, More...

MSC Cruises, MSC Musica

Deal link -> Special

8 Night - South America
Starting in Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil, Itajai, Brazil, Santos (Sao Paulo), Brazil
2027 Sails: Mar 7, More...

MSC Cruises, MSC Seaview

24 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Mindelo, Cape Verde, Funchal (Madeira Islands), Portugal, Lisbon (Cascais), Portugal, Casablanca (Marrakesh), Morocco, Malaga (Granada), Spain, Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy
2027 Sails: Mar 7, More...

MSC Cruises, MSC Seaview

21 Night - Msc Grand Voyages
Starting in Santos (Sao Paulo), Brazil, Rio De Janeiro, Brazil, Maceio, Brazil, Mindelo, Cape Verde, Funchal (Madeira Islands), Portugal, Lisbon (Cascais), Portugal, Casablanca (Marrakesh), Morocco, Malaga (Granada), Spain, Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain
2027 Sails: Mar 7, More...

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