South America Cruises
Cruises that visit South America
Cruises by region
See all South America River Cruises
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay
16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
21 Night - Panama Canal
Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
24 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Sep 28, More...19 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 28, More...
36 Night - South Pacific from Lautoka to Valparaiso
Starting in Lautoka, Somosomo, Ringgold Isles, Cobia, Fulaga, Neiafu, Eueiki Island, Uoleva Island, Date Line gain a day, Rarotonga, Aitutaki, Bora Bora, Tikehau, Rangiroa, Papeete, Fakarava, Atuona / Hiva Oa, Tahuata, Hatiheu, Hanavave, Mangareva, Adamstown, Easter Island, Alexander Selkirk Island, Robinson Crusoe Island, Valparaiso
2026 Sails: Sep 29, More...
17 Night - Panama Canal Eastbound Cruise
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, Ocho Rios, Jamaica, George Town, Grand Cayman, Tampa, Florida
2026 Sails: Oct 1, More...16 Night - Panama Canal
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 2, More...
31 Night - Across Oceanic Cultures : Fiji to the Chilean Coast
Starting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile
2026 Sails: Oct 4, More...69 Night - Fiji to the Chilean Coast & An - Tour P29
Starting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile, Scenic Cruising Reloncavi Sound, Puerto Montt, Chile, Scenic cruising Moraleda Channel, Scenic cruising Darwin Channel, Scenic cruising Baker Channel, Caleta Tortel, Chile, Transit the English Narrows, Scenic cruising Eyre Fjord, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Wide Channel, Scenic cruising Peel Fjord, Brujo Glacier, Chile, Scenic cruising Smyth Channel, Strait of Magellan, Punta Arenas, Chile, Antarctica, Ushuaia, Argentina, Antarctica, South Georgia, The Falkland Islands, Ushuaia, Argentina, Buenos Aires
2026 Sails: Oct 4, More...49 Night - Fiji to the Chilean Coast & An - Tour P28
Starting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile, Scenic Cruising Reloncavi Sound, Puerto Montt, Chile, Scenic cruising Moraleda Channel, Scenic cruising Darwin Channel, Scenic cruising Baker Channel, Caleta Tortel, Chile, Transit the English Narrows, Scenic cruising Eyre Fjord, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Wide Channel, Scenic cruising Peel Fjord, Brujo Glacier, Chile, Scenic cruising Smyth Channel, Strait of Magellan, Punta Arenas, Chile, Antarctica, Ushuaia, Argentina, Buenos Aires
2026 Sails: Oct 4, More...
Cruises that visit South America
Cruises by region
See all South America River Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay
16 Night - Journeys - Panama CanalStarting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
21 Night - Panama CanalStarting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
24 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Sep 28, More...
19 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 28, More...
36 Night - South Pacific from Lautoka to ValparaisoStarting in Lautoka, Somosomo, Ringgold Isles, Cobia, Fulaga, Neiafu, Eueiki Island, Uoleva Island, Date Line gain a day, Rarotonga, Aitutaki, Bora Bora, Tikehau, Rangiroa, Papeete, Fakarava, Atuona / Hiva Oa, Tahuata, Hatiheu, Hanavave, Mangareva, Adamstown, Easter Island, Alexander Selkirk Island, Robinson Crusoe Island, Valparaiso
2026 Sails: Sep 29, More...
17 Night - Panama Canal Eastbound CruiseStarting in Los Angeles, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, Ocho Rios, Jamaica, George Town, Grand Cayman, Tampa, Florida
2026 Sails: Oct 1, More...
16 Night - Panama CanalStarting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 2, More...
31 Night - Across Oceanic Cultures : Fiji to the Chilean CoastStarting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile
2026 Sails: Oct 4, More...
69 Night - Fiji to the Chilean Coast & An - Tour P29Starting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile, Scenic Cruising Reloncavi Sound, Puerto Montt, Chile, Scenic cruising Moraleda Channel, Scenic cruising Darwin Channel, Scenic cruising Baker Channel, Caleta Tortel, Chile, Transit the English Narrows, Scenic cruising Eyre Fjord, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Wide Channel, Scenic cruising Peel Fjord, Brujo Glacier, Chile, Scenic cruising Smyth Channel, Strait of Magellan, Punta Arenas, Chile, Antarctica, Ushuaia, Argentina, Antarctica, South Georgia, The Falkland Islands, Ushuaia, Argentina, Buenos Aires
2026 Sails: Oct 4, More...
49 Night - Fiji to the Chilean Coast & An - Tour P28Starting in Lautoka, Fiji, Kadavu, Fiji, Vulaga, Fiji, Vavau, Tonga, Nukupule Island, Haapai Group, Tonga, Apia, Upolu, Samoa, Cross International Dateline, Aitutaki, Cook Islands, Raiatea, Society Islands, French Polynesia, Maroe Bay, Huahine Iti, French Polynesia, Papeete, French Polynesia, Anaa, French Polynesia, Toau, French Polynesia, Fakarava, Tuamotu, French Polynesia, Adamstown, Pitcairn Island, Pitcairn, Ducie Island, Pitcairn, Easter Island, Chile, Juan Fernandez, San Antonio CL (Santiago), Chile, Scenic Cruising Reloncavi Sound, Puerto Montt, Chile, Scenic cruising Moraleda Channel, Scenic cruising Darwin Channel, Scenic cruising Baker Channel, Caleta Tortel, Chile, Transit the English Narrows, Scenic cruising Eyre Fjord, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Wide Channel, Scenic cruising Peel Fjord, Brujo Glacier, Chile, Scenic cruising Smyth Channel, Strait of Magellan, Punta Arenas, Chile, Antarctica, Ushuaia, Argentina, Buenos Aires
2026 Sails: Oct 4, More...
