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Central America Cruises

Cruises that visit Central America

Cruises by region

See all Central America River Cruises

Click on a cruise ship itinerary in Central America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Central America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Belize : Costa Rica : El Salvador : Guatemala : Honduras : Nicaragua : Panama

Central America
Cruise Specials

Windstar, Star Seeker
Star Seeker8 Night - Creatures & Cultures of Costa Rica & Mexico
Starting in Puerto Caldera, Curu, Costa Rica, Playas del Coco, Puerto Chiapas, Huatulco, Puerto Vallarta
2026 Sails: Apr 20, More...
Royal Caribbean, Radiance of the Seas
Radiance of the Seas8 Night - Western Caribbean Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Cozumel, Mexico, Roatan, Honduras, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Apr 22, More...
MSC Cruises, MSC Poesia
MSC Poesia18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 23, More...
MSC Cruises, MSC Poesia
MSC Poesia14 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Apr 23, More...
Oceania Cruises, Oceania Insignia
Oceania Insignia10 Night - Canal & Coral Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
MSC Cruises, MSC World America
MSC World America7 Night - Caribbean and Antilles
Starting in Miami, Florida, Roatan Island, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 25, More...
MSC Cruises, MSC World America
MSC World America14 Night - Caribbean and Antilles
Starting in Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 25, 2027: Mar 13, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
Royal Caribbean, Enchantment of the Seas
Enchantment of the Seas7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Roatan, Honduras, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Apr 25, More...

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Central America Cruises