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Central America Cruises

Cruises that visit Central America

Cruises by region

See all Central America River Cruises

Click on a cruise ship itinerary in Central America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Central America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Belize : Costa Rica : El Salvador : Guatemala : Honduras : Nicaragua : Panama

Central America
Cruise Specials

Princess Cruises, Regal Princess
Regal Princess7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Roatan (Isla Tropicale), Honduras, Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Sep 19, More...
Royal Caribbean, Enchantment of the Seas
Enchantment of the Seas7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Roatan, Honduras, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, Tampa, Florida
2026 Sails: Sep 19, More...
Princess Cruises, Island Princess
Island Princess16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 20, More...
Royal Caribbean, Star of the Seas
Star of the Seas7 Night - Western Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Sep 20, More...
Princess Cruises, Coral Princess
Coral Princess22 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 23, More...
Cunard Line, Queen Elizabeth
Queen Elizabeth21 Night - Seattle to Miami
Starting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Sep 24, More...
Carnival Cruise Lines, Carnival Miracle
Carnival Miracle16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
Margaritaville at Sea, Margaritaville Islander
Margaritaville Islander7 Night - Key West & Western Caribbean
Starting in Port Tampa Bay, Key West, FL, Roatan, Honduras, Belize City, Belize, Cozumel, Mexico, Port Tampa Bay
2026 Sails: Sep 26, Oct 17, 2027: Oct 2, More...
Princess Cruises, Regal Princess
Regal Princess14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, San Juan, Puerto Rico, St Maarten, Fort Lauderdale, Florida, Roatan (Isla Tropicale), Honduras, Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Sep 26, More...
Icon of the Seas7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Sep 26, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 22, Jun 12, Jul 3, Jul 24, More...

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Central America Cruises