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South Africa Cruise Departures

Cruises that depart from Africa: South Africa

Cruises that visit South Africa

See all River Cruises that depart from South Africa

Click on a cruise ship itinerary sailing from South Africa (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Africa), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Cape Town : Durban : Johannesburg

Departing from
South Africa
Cruise Specials

Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa Cruise Ship17 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona
2026 Sails: Mar 18, More...
PONANT, Le Bougainville
Le Bougainville Cruises10 Night - South Africa and Namibia by Sea : Around the Cape of Good Hope - with Smithsonian Journeys
Starting in Durban, East London, Port Elizabeth, Cape Town, Luderitz, Walvis Bay
2026 Sails: Mar 19, More...
Swan Hellenic Cruises, SH Diana
SH Diana Cruises11 Night - Cruising in Namibia : the Skeleton Coast
Starting in Cape Town, Saldanha Bay, Langebaan, Luderitz, Walvis Bay, Ilha Baia Dos Tigres, Namibe, Luanda
2026 Sails: Mar 25, More...
MSC Cruises, MSC Opera
MSC Opera Cruise Ship3 Night - Dur
Starting in Durban, South Africa, Cape Town, South Africa
2026 Sails: Mar 27, More...
Silversea Cruises, Silver Cloud Expedition
Silver Cloud Expedition Cruises20 Night - Cape Town to Mahe
Starting in Cape Town, Port Elizabeth ZA, Richards Bay, Bazaruto Island, Island of Mozambique, Kilwa Kisiwani, Sinda Island, Misali Island, Zanzibar, Assumption, Aldabra, La Digue, Mahe
2026 Sails: Mar 27, More...
Oceania Sirena Cruises24 Night - African Revelation
Starting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2026 Sails: Mar 31, 2027: Feb 7, More...
MSC Cruises, MSC Opera
MSC Opera Cruise Ship5 Night - Cpt
Starting in Cape Town, South Africa, Walvis Bay, Namibia, Cape Town, South Africa
2026 Sails: Apr 4, More...
Cunard Line, Queen Mary 2
Queen Mary 2 Cruise Ship25 Night - Cape Town to New York
Starting in Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK, Le Havre, France, New York, NY
2026 Sails: Apr 13, More...
Cunard Line, Queen Mary 2
Queen Mary 2 Cruise Ship17 Night - Cape Town to Southampton
Starting in Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK
2026 Sails: Apr 13, More...
Silversea Cruises, Silver Dawn
Silver Dawn Cruises23 Night - Cape Town to Lisbon
Starting in Cape Town, Luderitz, Walvis Bay, Luanda, Banjul, Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal, Madeira, Portimao, Lisbon
2026 Sails: May 4, More...

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South Africa Cruise Departures