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South Africa Cruise Departures

Cruises that depart from Africa: South Africa

Cruises that visit South Africa

See all River Cruises that depart from South Africa

Click on a cruise ship itinerary sailing from South Africa (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Africa), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Cape Town : Durban : Johannesburg

Departing from
South Africa
Cruise Specials

Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa24 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona, Civitavecchia, Corfu, Bari, Trieste
2026 Sails: Mar 18, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa19 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona
2026 Sails: Mar 18, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa18 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille
2026 Sails: Mar 18, More...
MSC Cruises, MSC Opera
MSC Opera4 Night - South Africa
Starting in Durban, South Africa, Maputo, Mozambique, Portuguese Island (Inhaca Archipelago), Mozambique, Durban, South Africa
2026 Sails: Mar 23, More...
Swan Hellenic, SH Diana
SH Diana11 Night - Cruising in Namibia : the Skeleton Coast
Starting in Cape Town, Saldanha Bay, Langebaan, Luderitz, Walvis Bay, Ilha Baia Dos Tigres, Namibe, Luanda
2026 Sails: Mar 25, More...
MSC Opera3 Night - South Africa
Starting in Durban, South Africa, Cape Town, South Africa
2026 Sails: Mar 27, More...
Silversea, Silver Cloud
Silver Cloud20 Night - Cape Town to Mahe
Starting in Cape Town, Port Elizabeth ZA, Richards Bay, Bazaruto Island, Island of Mozambique, Kilwa Kisiwani, Sinda Island, Misali Island, Zanzibar, Assumption, Aldabra, La Digue, Mahe
2026 Sails: Mar 27, More...
Oceania Sirena24 Night - African Revelation
Starting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2026 Sails: Mar 31, 2027: Feb 7, More...
AmaWaterways Tours, Zambezi Queen Tours
Zambezi Queen Tours14 Night - Rivers & Rails of Africa with Cape Town, Safari Cruise, Victoria Falls, Rovos Rail
Starting in Cape Town, Victoria Falls, Rovos Rail, Pretoria, Johannesburg
2026 Sails: Apr 3, May 8, Nov 13, 2027: Apr 2, Apr 9, Jul 23, Jul 30, Aug 6, Aug 13, Oct 29, Nov 5, More...

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South Africa Cruise Departures