South Africa Cruise Departures
Cruises that depart from Africa: South Africa
Cruises that visit South Africa
See all River Cruises that depart from South Africa
Related areas: Cape Town : Durban : Johannesburg
9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls
Starting in Cape Town, Victoria Falls, Johannesburg
2026 Sails: Feb 6, Mar 6, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, Oct 1, Oct 8, Oct 15, Oct 29, More...15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National Park
Starting in Cape Town, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 6, Mar 6, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, Oct 1, Oct 8, Oct 15, Oct 29, More...17 Night - Golden Trails of East Africa with Cruise and Land Package : Johannesburg, Wildlife Cruise, Victoria Falls, Johannesburg and Tanzania
Starting in Johannesburg, Victoria Falls, Johannesburg, Arusha, Tarangire, Lake Manyara, Ngorongoro, Serengeti National Park, Arusha
2026 Sails: Feb 8, Mar 8, Aug 2, 2027: Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, Apr 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 10, Oct 17, Oct 31, More...12 Night - Wildlife & the Falls with Cruise and Land Package : Johannesburg, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National Park
Starting in Johannesburg, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 8, Mar 8, Aug 2, 2027: Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, Apr 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 10, Oct 17, Oct 31, More...
23 Night - West African Adventure
Starting in Cape Town, Cruising the South Atlantic Ocean, Walvis Bay, Cruising the South Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Cruising the North Atlantic Ocean, Banjul, Cruising the North Atlantic Ocean, Mindelo (Porto Grande), Cruising the North Atlantic Ocean, Santa Cruz de Tenerife, Santa Cruz de La Palma, Cruising the North Atlantic Ocean, Lisbon
2026 Sails: Feb 28, More...
24 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona, Civitavecchia, Corfu, Bari, Trieste
2026 Sails: Mar 18, More...19 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona
2026 Sails: Mar 18, More...18 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille
2026 Sails: Mar 18, More...17 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona
2026 Sails: Mar 18, More...
Cruises that depart from Africa: South Africa
Cruises that visit South Africa
See all River Cruises that depart from South Africa
Click on a cruise ship itinerary sailing from South Africa (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Africa), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Cape Town : Durban : Johannesburg
9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria FallsStarting in Cape Town, Victoria Falls, Johannesburg
2026 Sails: Feb 6, Mar 6, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, Oct 1, Oct 8, Oct 15, Oct 29, More...
15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National ParkStarting in Cape Town, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 6, Mar 6, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, Oct 1, Oct 8, Oct 15, Oct 29, More...
17 Night - Golden Trails of East Africa with Cruise and Land Package : Johannesburg, Wildlife Cruise, Victoria Falls, Johannesburg and TanzaniaStarting in Johannesburg, Victoria Falls, Johannesburg, Arusha, Tarangire, Lake Manyara, Ngorongoro, Serengeti National Park, Arusha
2026 Sails: Feb 8, Mar 8, Aug 2, 2027: Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, Apr 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 10, Oct 17, Oct 31, More...
12 Night - Wildlife & the Falls with Cruise and Land Package : Johannesburg, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National ParkStarting in Johannesburg, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 8, Mar 8, Aug 2, 2027: Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, Apr 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 10, Oct 17, Oct 31, More...
23 Night - West African AdventureStarting in Cape Town, Cruising the South Atlantic Ocean, Walvis Bay, Cruising the South Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Cruising the North Atlantic Ocean, Banjul, Cruising the North Atlantic Ocean, Mindelo (Porto Grande), Cruising the North Atlantic Ocean, Santa Cruz de Tenerife, Santa Cruz de La Palma, Cruising the North Atlantic Ocean, Lisbon
2026 Sails: Feb 28, More...
24 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona, Civitavecchia, Corfu, Bari, Trieste
2026 Sails: Mar 18, More...
19 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona
2026 Sails: Mar 18, More...
18 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille
2026 Sails: Mar 18, More...
17 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona
2026 Sails: Mar 18, More...
