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Cape Town Cruise Departures

Cruises that depart from Africa: South Africa: Cape Town

Cruises that visit Cape Town

See all River Cruises that depart from Cape Town

Click on a cruise ship itinerary sailing from Cape Town (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Town), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Zambezi Queen Cruise Tours14 Night - Stars of South Africa Cruise Tour from Cape Town to Johannesburg
Starting in Cape Town; with stops in Chobe National Park; Victoria Falls; Johannesburg; Kruger National Park
2021 Sails: Apr 16, Apr 23, Apr 30, May 14, May 21, May 28, Jun 11, Jun 25, Jul 2, Jul 16, Jul 23, Jul 30, Aug 13, Aug 27, Sep 3, Sep 10, Sep 17, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...
Zambezi Queen Cruises9 Night - Discover Africa : 3 Nights Capetown, 4-Night Safari Cruise, 2 Nights Victoria Falls : Cape Town to Johannesburg : ms Zambezi Queen
Starting in Cape Town with stops in Kasane, Zambezi Queen, Victoria Falls, Johannesburg
2021 Sails: Jun 11, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 3, Sep 10, Sep 17, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...
Zambezi Queen Cruises14 Night - Stars of South Africa : 3 Nights Cape Town, 4-Night Safari Cruise, 2 Nights Victoria Falls, 2 Nights Johannesburg, 3 Nights Greater Kruger National Park : Cape Town to Johannesburg : ms Zambezi Queen
Starting in Cape Town with stops in Kasane, Zambezi Queen, Victoria Falls, Johannesburg, Kruger National Park Area
2021 Sails: Jun 11, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 3, Sep 10, Sep 17, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...
Zambezi Queen Cruises12 Night - Rivers & Rails of Africa : 3 Nights Cape Town, 4-Night Safari Cruise, 2 Nights Victoria Falls, 3 Nights Rovos Rail : Cape Town to Johannesburg : ms Zambezi Queen
Starting in Cape Town with stops in Zambezi Queen, Victoria Falls, Rovos Rail, Pretoria
2021 Sails: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 3, Sep 10, Sep 17, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, More...
Seven Seas Voyager Cruise Ship16 Night - Cape Town South Africa to Cape Town South Africa on Seven Seas Voyager
Starting in Cape Town with stops in Cruising the Atlantic Ocean, Walvis Bay, Namibia, Cruising The Cape Of Good Hope, Port Elizabeth, Durban, Cruising the Indian Ocean, Maputo, Richards Bay, Mossel Bay
2021 Sails: Nov 21, More...
Seven Seas Voyager Cruise Ship15 Night - Cape Town South Africa to Cape Town South Africa on Seven Seas Voyager
Starting in Cape Town with stops in Cruising the Atlantic Ocean, Walvis Bay, Cruising The Cape Of Good Hope, Port Elizabeth, Durban, Cruising the Indian Ocean, Maputo, Richards Bay, Mossel Bay
2021 Sails: Dec 7, More...
Azamara Pursuit Cruises13 Night - South Africa Intensive Voyage onboard Azamara Pursuit
Starting in Cape Town with stops in Port Elizabeth, East London, Maputo, Richards Bay, Durban
2021 Sails: Dec 21, More...
NCL Norwegian Jade Cruise Ship12 Night - Africa: South Africa & Namibia from Cape Town, South Africa
Starting in Cape Town with stops in Mossel Bay, Port Elizabeth, Richard's Bay, Durban, Luderitz, Walvis Bay
2021 Sails: Dec 21, 2022: Jan 2, Jan 14, Dec 21, 2023: Jan 2, Jan 14, More...
Seven Seas Voyager Cruise Ship14 Night - Cape Town South Africa to Rio De Janeiro Brazil on Seven Seas Voyager
Starting in Cape Town with stops in Cruising the Atlantic Ocean, Namibia, Walvis Bay, Jamestown, Rio de Janeiro
2021 Sails: Dec 22, More...
Azamara Pursuit Cruises12 Night - South Africa Intensive Voyage onboard Azamara Pursuit
Starting in Cape Town with stops in Port Elizabeth, East London, Maputo, Richards Bay, Durban
2022 Sails: Jan 3, More...


Cape Town Cruise Departures

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