Cape Town Cruise Departures
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
14 Night - Lagoons, Safaris & Dunes
Starting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Cruising the Cape of Good Hope, Port Elizabeth ZA, East London, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town
2026 Sails: Jan 13, More...16 Night - Shores of Madagascar
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, East London, Cruising the Indian Ocean, Maputo, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Nosy Boraha, Toamasina, Cruising the Indian Ocean, Port Louis
2026 Sails: Jan 27, More...
27 Night - Cape Town to Hong Kong
Starting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China
2026 Sails: Jan 31, More...
18 Night - West Africa Cruise : Walvis Bay, St. Helena & Senegal
Starting in Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Banjul, Dakar, Gran Canaria, Canary Islands
2026 Sails: Feb 3, More...
9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls
Starting in Cape Town, Victoria Falls, Johannesburg
2026 Sails: Feb 6, Mar 6, Apr 3, May 8, May 15, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jun 18, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, More...15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National Park
Starting in Cape Town, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 6, Mar 6, Apr 3, May 8, May 15, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jun 11, Jun 18, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, More...23 Night - West African Adventure
Starting in Cape Town, Cruising the South Atlantic Ocean, Walvis Bay, Cruising the South Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Cruising the North Atlantic Ocean, Banjul, Cruising the North Atlantic Ocean, Mindelo (Porto Grande), Cruising the North Atlantic Ocean, Santa Cruz de Tenerife, Santa Cruz de La Palma, Cruising the North Atlantic Ocean, Lisbon
2026 Sails: Feb 28, More...
19 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona
2026 Sails: Mar 18, More...18 Night - Round World from Cape Town
Starting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille
2026 Sails: Mar 18, More...
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
Click on a cruise ship itinerary sailing from Cape Town (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Town), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Lagoons, Safaris & DunesStarting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Cruising the Cape of Good Hope, Port Elizabeth ZA, East London, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town
2026 Sails: Jan 13, More...
Deal link -> Special
16 Night - Shores of MadagascarStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, East London, Cruising the Indian Ocean, Maputo, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Nosy Boraha, Toamasina, Cruising the Indian Ocean, Port Louis
2026 Sails: Jan 27, More...
27 Night - Cape Town to Hong KongStarting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China
2026 Sails: Jan 31, More...
18 Night - West Africa Cruise : Walvis Bay, St. Helena & SenegalStarting in Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Banjul, Dakar, Gran Canaria, Canary Islands
2026 Sails: Feb 3, More...
9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria FallsStarting in Cape Town, Victoria Falls, Johannesburg
2026 Sails: Feb 6, Mar 6, Apr 3, May 8, May 15, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jun 18, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, Sep 17, More...
15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National ParkStarting in Cape Town, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Feb 6, Mar 6, Apr 3, May 8, May 15, Jul 31, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, Jun 11, Jun 18, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, More...
Deal link -> Special
23 Night - West African AdventureStarting in Cape Town, Cruising the South Atlantic Ocean, Walvis Bay, Cruising the South Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Cruising the North Atlantic Ocean, Banjul, Cruising the North Atlantic Ocean, Mindelo (Porto Grande), Cruising the North Atlantic Ocean, Santa Cruz de Tenerife, Santa Cruz de La Palma, Cruising the North Atlantic Ocean, Lisbon
2026 Sails: Feb 28, More...
19 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille, Savona
2026 Sails: Mar 18, More...
18 Night - Round World from Cape TownStarting in Cape Town, Walvis Bay, St Vincent / Cape Verde / Mindelo, Las Palmas, Barcelona, Marseille
2026 Sails: Mar 18, More...
