Cape Town Cruise Departures
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
19 Night - Majestic Safaris & Modern Spires
Starting in Cape Town, Mossel Bay, Port Elizabeth ZA, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Cruising the Indian Ocean, Mahe, Cruising the Indian Ocean, Cruising the Arabian Sea, Muscat, Fujairah, Dubai, Doha
2025 Sails: Nov 25, More...
24 Night - Indian Ocean Opus
Starting in Cape Town, Mossel Bay, Durban, Maputo, Pointe Des Galets, Port Louis, Male, Colombo, Galle, Phuket, Penang, Kuala Lumpur (Port Klang), Singapore
2025 Sails: Dec 2, More...
26 Night - Africa & Indian Ocean
Starting in Cape Town, Mossel Bay, Port Elizabeth ZA, East London, Richards Bay, Maputo, Dar Es Salaam, Zanzibar, Mombasa, Mahe, Praslin, La Digue, Male, Colombo, Mormugao (Goa), Mumbai
2025 Sails: Dec 23, More...13 Night - Africa & Indian Ocean
Starting in Cape Town, Mossel Bay, Port Elizabeth ZA, East London, Richards Bay, Maputo, Dar Es Salaam, Zanzibar, Mombasa
2025 Sails: Dec 23, More...
14 Night - Lagoons, Safaris & Dunes
Starting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Cruising the Cape of Good Hope, Port Elizabeth ZA, East London, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town
2026 Sails: Jan 13, More...16 Night - Shores of Madagascar
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, East London, Cruising the Indian Ocean, Maputo, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Nosy Boraha, Toamasina, Cruising the Indian Ocean, Port Louis
2026 Sails: Jan 27, More...
45 Night - Cape Town to Sydney
Starting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia
2026 Sails: Jan 31, More...27 Night - Cape Town to Hong Kong
Starting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China
2026 Sails: Jan 31, More...22 Night - Cape Town to Singapore
Starting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore
2026 Sails: Jan 31, More...
18 Night - West Africa Cruise : Walvis Bay, St. Helena & Senegal
Starting in Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Banjul, Dakar, Gran Canaria, Canary Islands
2026 Sails: Feb 3, More...
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
Click on a cruise ship itinerary sailing from Cape Town (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Town), please visit: Cruise Search or try our Virtual Cruise Advisor™.
19 Night - Majestic Safaris & Modern SpiresStarting in Cape Town, Mossel Bay, Port Elizabeth ZA, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Cruising the Indian Ocean, Mahe, Cruising the Indian Ocean, Cruising the Arabian Sea, Muscat, Fujairah, Dubai, Doha
2025 Sails: Nov 25, More...
24 Night - Indian Ocean OpusStarting in Cape Town, Mossel Bay, Durban, Maputo, Pointe Des Galets, Port Louis, Male, Colombo, Galle, Phuket, Penang, Kuala Lumpur (Port Klang), Singapore
2025 Sails: Dec 2, More...
26 Night - Africa & Indian OceanStarting in Cape Town, Mossel Bay, Port Elizabeth ZA, East London, Richards Bay, Maputo, Dar Es Salaam, Zanzibar, Mombasa, Mahe, Praslin, La Digue, Male, Colombo, Mormugao (Goa), Mumbai
2025 Sails: Dec 23, More...
13 Night - Africa & Indian OceanStarting in Cape Town, Mossel Bay, Port Elizabeth ZA, East London, Richards Bay, Maputo, Dar Es Salaam, Zanzibar, Mombasa
2025 Sails: Dec 23, More...
14 Night - Lagoons, Safaris & DunesStarting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Cruising the Cape of Good Hope, Port Elizabeth ZA, East London, Durban, Cruising the Indian Ocean, Mossel Bay, Cape Town
2026 Sails: Jan 13, More...
16 Night - Shores of MadagascarStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, East London, Cruising the Indian Ocean, Maputo, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Nosy Boraha, Toamasina, Cruising the Indian Ocean, Port Louis
2026 Sails: Jan 27, More...
45 Night - Cape Town to SydneyStarting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China, Manila, Philippines, Bali, Indonesia, Darwin, NT, Australia, Airlie Beach, Australia, Brisbane, Australia, Sydney AU, Australia
2026 Sails: Jan 31, More...
27 Night - Cape Town to Hong KongStarting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore, Hong Kong, China
2026 Sails: Jan 31, More...
22 Night - Cape Town to SingaporeStarting in Cape Town, South Africa, Gqeberha (Port Elizabeth ZA), South Africa, Durban, South Africa, Le Port, Reunion, Port Louis, Mauritius, Colombo, Sri Lanka, Port Kelang (tours to Kuala Lumpur), Malaysia, Singapore
2026 Sails: Jan 31, More...
18 Night - West Africa Cruise : Walvis Bay, St. Helena & SenegalStarting in Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Banjul, Dakar, Gran Canaria, Canary Islands
2026 Sails: Feb 3, More...
