Cape Town Cruise Departures
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
20 Night - South Atlantic Cruise : from South Africa to Antarctica
Starting in Cape Town, Tristan da Cunha, South Georgia, Antarctic Peninsula, Ushuaia
2026 Sails: Oct 23, More...
14 Night - Rivers & Rails of Africa with Cape Town, Safari Cruise, Victoria Falls, Rovos Rail
Starting in Cape Town, Chobe River, Victoria Falls, Rovos Rail, Pretoria, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: May 7, 2028: Mar 3, Mar 17, Mar 31, Apr 7, May 5, Jun 9, Jul 7, Jul 21, Jul 28, Aug 4, Aug 11, Aug 25, Sep 1, More...15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National Park
Starting in Cape Town, Chobe River, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, May 7, Sep 3, Oct 15, Nov 5, Nov 12, Nov 19, More...9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls
Starting in Cape Town, Chobe River, Victoria Falls, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, May 7, Sep 3, Oct 15, Nov 5, Nov 12, Nov 19, More...
22 Night - Cape Town to Mumbai
Starting in Cape Town, Port Elizabeth ZA, East London, Durban, Pointe Des Galets, Port Louis, Mahe, Cochin, New Mangalore, Mumbai
2026 Sails: Nov 10, More...
15 Night - Madagascar Marvels
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis
2027 Sails: Feb 1, More...61 Night - Indian Ocean Odyssey
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis, Cruising the Indian Ocean, Praslin (La Digue), Cruising the Indian Ocean, Male, Cruising the Laccadive Sea, Colombo, Cruising the Laccadive Sea, Cochin (Kochi), Cruising the Arabian Sea, Mumbai (Bombay), Cruising the Arabian Sea, Salalah, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Aqaba, Luxor (Safaga), Suez Canal (Transit), Jerusalem (Haifa), Cruising the Mediterranean Sea, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Portofino, Cannes, Cruising the Mediterranean Sea, Mahon, Minorca, Palma De Mallorca, Ibiza, Cruising the Balearic Sea, Valencia, Barcelona
2027 Sails: Feb 1, More...
24 Night - Gold & Ivory Coasts
Starting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2027 Sails: Feb 7, More...12 Night - Iconic Africa with Cruise and Land Package : in Cape Town, Wildlife Cruise, in Victoria Falls, Johannesburg and at Tented Safari Lodge in Greater Kruger National Park
Starting in Cape Town, Chobe River, Victoria Falls, Johannesburg, Kruger Park
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Oct 19, Nov 2, Nov 16, Nov 23, 2028: Mar 7, Mar 21, Mar 28, Apr 4, Apr 11, Apr 18, May 2, May 16, May 23, More...11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria Falls
Starting in Cape Town, Chobe River, Victoria Falls, Johannesburg
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Oct 19, Nov 2, Nov 16, Nov 23, 2028: Mar 7, Mar 21, Mar 28, Apr 4, Apr 11, Apr 18, May 2, May 16, May 23, More...
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
Click on a cruise ship itinerary sailing from Cape Town (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Town), please visit: Cruise Search or try our Virtual Cruise Advisor™.
20 Night - South Atlantic Cruise : from South Africa to AntarcticaStarting in Cape Town, Tristan da Cunha, South Georgia, Antarctic Peninsula, Ushuaia
2026 Sails: Oct 23, More...
14 Night - Rivers & Rails of Africa with Cape Town, Safari Cruise, Victoria Falls, Rovos RailStarting in Cape Town, Chobe River, Victoria Falls, Rovos Rail, Pretoria, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: May 7, 2028: Mar 3, Mar 17, Mar 31, Apr 7, May 5, Jun 9, Jul 7, Jul 21, Jul 28, Aug 4, Aug 11, Aug 25, Sep 1, More...
15 Night - Stars of South Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria Falls, Johannesburg, Greater Kruger National ParkStarting in Cape Town, Chobe River, Victoria Falls, Johannesburg, Kruger Park, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, May 7, Sep 3, Oct 15, Nov 5, Nov 12, Nov 19, More...
9 Night - Discover Africa with Cruise and Land Package : Cape Town, Wildlife Cruise, Victoria FallsStarting in Cape Town, Chobe River, Victoria Falls, Johannesburg
2026 Sails: Oct 30, Nov 6, 2027: Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, May 7, Sep 3, Oct 15, Nov 5, Nov 12, Nov 19, More...
22 Night - Cape Town to MumbaiStarting in Cape Town, Port Elizabeth ZA, East London, Durban, Pointe Des Galets, Port Louis, Mahe, Cochin, New Mangalore, Mumbai
2026 Sails: Nov 10, More...
15 Night - Madagascar MarvelsStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis
2027 Sails: Feb 1, More...
61 Night - Indian Ocean OdysseyStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis, Cruising the Indian Ocean, Praslin (La Digue), Cruising the Indian Ocean, Male, Cruising the Laccadive Sea, Colombo, Cruising the Laccadive Sea, Cochin (Kochi), Cruising the Arabian Sea, Mumbai (Bombay), Cruising the Arabian Sea, Salalah, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Aqaba, Luxor (Safaga), Suez Canal (Transit), Jerusalem (Haifa), Cruising the Mediterranean Sea, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Portofino, Cannes, Cruising the Mediterranean Sea, Mahon, Minorca, Palma De Mallorca, Ibiza, Cruising the Balearic Sea, Valencia, Barcelona
2027 Sails: Feb 1, More...
24 Night - Gold & Ivory CoastsStarting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2027 Sails: Feb 7, More...
12 Night - Iconic Africa with Cruise and Land Package : in Cape Town, Wildlife Cruise, in Victoria Falls, Johannesburg and at Tented Safari Lodge in Greater Kruger National ParkStarting in Cape Town, Chobe River, Victoria Falls, Johannesburg, Kruger Park
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Oct 19, Nov 2, Nov 16, Nov 23, 2028: Mar 7, Mar 21, Mar 28, Apr 4, Apr 11, Apr 18, May 2, May 16, May 23, More...
11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria FallsStarting in Cape Town, Chobe River, Victoria Falls, Johannesburg
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Oct 19, Nov 2, Nov 16, Nov 23, 2028: Mar 7, Mar 21, Mar 28, Apr 4, Apr 11, Apr 18, May 2, May 16, May 23, More...
