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Santos Cruise Departures

Cruises that depart from South America: Brazil: Santos

Cruises that visit Santos

Click on a cruise ship itinerary sailing from Santos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santos), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MSC Cruises, MSC Virtuosa
MSC Virtuosa Cruises4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa Cruises3 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil
2026 Sails: Dec 5, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Salvador, Brazil, Maceio, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 5, Dec 19, 2027: Jan 2, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, More...
MSC Cruises, MSC Lirica
MSC Lirica Cruise Ship6 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Buzios, Brazil, Paranagua, Brazil
2026 Sails: Dec 6, More...
MSC Cruises, MSC Musica
MSC Musica Cruise Ship8 Night - South America
Starting in Santos (Sao Paulo), Brazil, Montevideo, Uruguay, Buenos Aires, Argentina, Punta Del Este, Uruguay, Santos (Sao Paulo), Brazil
2026 Sails: Dec 20, 2027: Jan 6, Jan 14, More...
MSC Cruises, MSC Musica
MSC Musica Cruise Ship9 Night - South America
Starting in Santos (Sao Paulo), Brazil, Montevideo, Uruguay, Punta Del Este, Uruguay, Buenos Aires, Argentina, Camboriu, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 28, More...
MSC Cruises, MSC Musica
MSC Musica Cruise Ship4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2027 Sails: Jan 25, Feb 5, Mar 22, More...
MSC Cruises, MSC Divina
MSC Divina Cruises7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2027 Sails: Jan 31, More...
MSC Cruises, MSC Musica
MSC Musica Cruise Ship4 Night - South America
Starting in Santos (Sao Paulo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, Santos (Sao Paulo), Brazil
2027 Sails: Feb 1, Feb 12, Feb 22, Mar 8, Mar 15, More...
MSC Cruises, MSC Divina
MSC Divina Cruises7 Night - Ssz
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2027 Sails: Feb 7, Feb 14, Feb 28, Mar 7, More...

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Santos Cruise Departures