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Rome Cruise Departures

Cruises that depart from Mediterranean: Italy: Rome

Cruises that visit Rome

See all River Cruises that depart from Rome

Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Avalon View Tours16 Night - Italian Vista with Romantic Rhine and in Lucerne
Starting in Arrive in Rome, Italy, Rome, Rome / Orvieto / Assisi / Perugia, Perugia / Florence / Padua, Padua Excursion to Venice, Padua / Verona / Milan, Milan Excursion to Lake Como, Milan / Lucerne, Switzerland, Lucerne, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: May 16, May 30, Jun 27, Aug 8, Aug 22, Sep 5, Oct 3, 2028: May 21, Jun 4, Jun 18, More...
SeaDream II7 Night - Cruise from Rome (Civitavecchia) to Nice
Starting in Rome (Civitavecchia), Porto Cervo, Sardinia, Bonifacio, Corsica, Calvi, Corsica, Monte Carlo, St Tropez, Cannes, Nice
2027 Sails: May 16, More...
Seven Seas Splendor14 Night - Splendid Atlantic Sojourn
Starting in Rome (Civitavecchia), Cruising the Mediterranean Sea, Barcelona (Tarragona), Alicante, Malaga, Casablanca, Cruising the Atlantic Ocean, Halifax, Cruising the Atlantic Ocean, New York
2027 Sails: May 18, More...
Viking Jupiter7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Corsica (Ajaccio), Monte Carlo, Marseille, Barcelona, Barcelona (Tarragona)
2027 Sails: May 19, More...
Viking Vesta7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2027 Sails: May 20, More...
Evrima7 Night - Rome (Civitavecchia) / Monte Carlo
Starting in Rome (Civitavecchia), Porto Santo Stefano, Portoferraio, Elba, Livorno, Portofino, Cannes, Saint-Tropez, Monte Carlo
2027 Sails: May 21, More...
Viking Mars7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2027 Sails: May 22, 2029: May 8, More...
Celebrity Ascent11 Night - Greece, Turkey & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Santorini, Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2027 Sails: May 24, Aug 16, Sep 27, More...
Oceania Sirena9 Night - Mysteries of History
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Syracuse IT (Sicily), Katakolon, Gythion, Mykonos, Skiathos, Canakkale (Troy), Istanbul
2027 Sails: May 24, More...
Explorer of the Seas7 Night - Italy, Spain & French Riviera
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Santa Margherita, Italy, Nice (Villefranche), France, Provence (Marseille), France, Palma De Mallorca, Spain, Barcelona, Spain
2027 Sails: May 24, Jun 14, Jul 26, Sep 6, More...


Rome Cruise Departures