Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
7 Night - Mediterranean Wayfarer
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Corfu, Kotor, Split, Zadar, Trieste
2026 Sails: Jun 6, More...
11 Night - Best of Italy & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: Jun 8, Jun 29, Aug 10, More...
7 Night - A Journey to Ancient Marvels & Sparkling Shorelines
Starting in Rome (Civitavecchia), Sorrento, Naxos (Taormina), Sicily, La Valletta, Tunis / La Goulette, Palma De Mallorca, Barcelona
2026 Sails: Jun 8, More...
7 Night - Essential Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Portofino, Monte Carlo, Toulon, Sete, Palma De Mallorca, Barcelona
2026 Sails: Jun 9, More...
14 Night - Italy, the Adriatic & Greece
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice, Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Jun 9, Aug 4, 2027: Mar 26, More...7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice
2026 Sails: Jun 9, Aug 4, 2027: Mar 26, More...21 Night - Adriatic & Mediterranean Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice, Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Jun 9, Aug 4, More...
7 Night - Rome (Civitavecchia) / Venice
Starting in Rome (Civitavecchia), Sorrento, Palermo, Sicily, Taormina (Naxos), Sicily, Dubrovnik, Croatia, Zadar, Venice
2026 Sails: Jun 10, More...
7 Night - Italy, Spain & French Riviera
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Santa Margherita, Italy, Nice (Villefranche), France, Provence (Marseille), France, Ibiza, Spain, Barcelona, Spain
2026 Sails: Jun 15, More...
10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Corfu, Greece, Olympia (Katakolon), Greece, Montenegro, Dubrovnik, Croatia, Split, Croatia, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jun 26, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
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7 Night - Mediterranean WayfarerStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Corfu, Kotor, Split, Zadar, Trieste
2026 Sails: Jun 6, More...
11 Night - Best of Italy & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: Jun 8, Jun 29, Aug 10, More...
7 Night - A Journey to Ancient Marvels & Sparkling ShorelinesStarting in Rome (Civitavecchia), Sorrento, Naxos (Taormina), Sicily, La Valletta, Tunis / La Goulette, Palma De Mallorca, Barcelona
2026 Sails: Jun 8, More...
7 Night - Essential MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Portofino, Monte Carlo, Toulon, Sete, Palma De Mallorca, Barcelona
2026 Sails: Jun 9, More...
14 Night - Italy, the Adriatic & GreeceStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice, Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Jun 9, Aug 4, 2027: Mar 26, More...
7 Night - Italian SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice
2026 Sails: Jun 9, Aug 4, 2027: Mar 26, More...
21 Night - Adriatic & Mediterranean SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice, Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Jun 9, Aug 4, More...
7 Night - Rome (Civitavecchia) / VeniceStarting in Rome (Civitavecchia), Sorrento, Palermo, Sicily, Taormina (Naxos), Sicily, Dubrovnik, Croatia, Zadar, Venice
2026 Sails: Jun 10, More...
7 Night - Italy, Spain & French RivieraStarting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Santa Margherita, Italy, Nice (Villefranche), France, Provence (Marseille), France, Ibiza, Spain, Barcelona, Spain
2026 Sails: Jun 15, More...
10 Night - Italy, Greece & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Corfu, Greece, Olympia (Katakolon), Greece, Montenegro, Dubrovnik, Croatia, Split, Croatia, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jun 26, More...
