Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
15 Night - Italy & Spain Transatlantic
Starting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Cagliari, Sardinia, Italy, Malaga, Spain, Casablanca, Morocco, Royal Naval Dockyard, Bermuda, Fort Lauderdale, Florida
2028 Sails: Oct 16, More...
13 Night - Italia to Iberian Treasures
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Tunis (La Goulette), Cagliari (Sardinia), Alicante, Cartagena ES, Melilla, Malaga, Seville (Cadiz), Lisbon
2028 Sails: Oct 19, More...28 Night - Iberian & Tropical Discovery
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Tunis (La Goulette), Cagliari (Sardinia), Alicante, Cartagena ES, Melilla, Malaga, Seville (Cadiz), Lisbon, Portimao, Funchal (Madeira), Santa Cruz de Tenerife, Santa Cruz de La Palma, San Juan, Miami
2028 Sails: Oct 19, More...
7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2028 Sails: Oct 20, More...
9 Night - Italian & French Riviera
Starting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Palma De Mallorca, Spain, Barcelona, Spain
2028 Sails: Oct 24, More...
20 Night - Mediterranean & Atlantic Crossing
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Valencia, Sail the Strait of Gibraltar, Seville (Cadiz), Sail the Atlantic Ocean, Madeira (Funchal), Sail the Atlantic Ocean, Philipsburg, San Juan
2028 Sails: Oct 25, More...
11 Night - Ionian & Aegean Wonders
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Katakolon, Gythion, Santorini, Rhodes, Patmos, Mykonos, Athens (Piraeus)
2028 Sails: Oct 26, More...
11 Night - Italy, Grek Isles & Malta
Starting in Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Palermo), Italy, Santorini, Greece, Athens (Piraeus), Greece, Rhodes, Greece, Mykonos, Greece, Valletta, Malta, Barcelona, Spain
2028 Sails: Oct 27, More...
7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2028 Sails: Oct 27, More...
21 Night - Mediterranean to Caribbean Sojourn
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Valencia, Sail the Strait of Gibraltar, Seville (Cadiz), Casablanca, Sail the Atlantic Ocean, Philipsburg, San Juan
2028 Sails: Oct 30, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Italy & Spain TransatlanticStarting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Cagliari, Sardinia, Italy, Malaga, Spain, Casablanca, Morocco, Royal Naval Dockyard, Bermuda, Fort Lauderdale, Florida
2028 Sails: Oct 16, More...
13 Night - Italia to Iberian TreasuresStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Tunis (La Goulette), Cagliari (Sardinia), Alicante, Cartagena ES, Melilla, Malaga, Seville (Cadiz), Lisbon
2028 Sails: Oct 19, More...
28 Night - Iberian & Tropical DiscoveryStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Tunis (La Goulette), Cagliari (Sardinia), Alicante, Cartagena ES, Melilla, Malaga, Seville (Cadiz), Lisbon, Portimao, Funchal (Madeira), Santa Cruz de Tenerife, Santa Cruz de La Palma, San Juan, Miami
2028 Sails: Oct 19, More...
7 Night - Journey to AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2028 Sails: Oct 20, More...
Deal link -> Special
9 Night - Italian & French RivieraStarting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Palma De Mallorca, Spain, Barcelona, Spain
2028 Sails: Oct 24, More...
20 Night - Mediterranean & Atlantic CrossingStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Valencia, Sail the Strait of Gibraltar, Seville (Cadiz), Sail the Atlantic Ocean, Madeira (Funchal), Sail the Atlantic Ocean, Philipsburg, San Juan
2028 Sails: Oct 25, More...
11 Night - Ionian & Aegean WondersStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Katakolon, Gythion, Santorini, Rhodes, Patmos, Mykonos, Athens (Piraeus)
2028 Sails: Oct 26, More...
11 Night - Italy, Grek Isles & MaltaStarting in Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Palermo), Italy, Santorini, Greece, Athens (Piraeus), Greece, Rhodes, Greece, Mykonos, Greece, Valletta, Malta, Barcelona, Spain
2028 Sails: Oct 27, More...
7 Night - Italian SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2028 Sails: Oct 27, More...
21 Night - Mediterranean to Caribbean SojournStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Valencia, Sail the Strait of Gibraltar, Seville (Cadiz), Casablanca, Sail the Atlantic Ocean, Philipsburg, San Juan
2028 Sails: Oct 30, More...
