Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
7 Night - Italy, France & Spain Cruise : Rome, Nice & Barcelona
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Nice, Provence (Marseille), Barcelona
2027 Sails: Dec 4, More...15 Night - Italy, France & Spain Combination Cruise : Rome, Barcelona & Seville
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Nice, Provence (Marseille), Barcelona, Valencia, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon
2027 Sails: Dec 4, More...
14 Night - Cities of Antiquity
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Valletta, Sail the Ionian Sea, Corfu (Kerkyra), Katakolon (Olympia), Kalamata, Crete (Heraklion), Rhodes, Santorini (Thira), Athens (Piraeus)
2027 Sails: Dec 7, More...
20 Night - Atlantic & Mediterranean Horizons
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Sail the Mediterranean Sea, Sail the Atlantic Ocean, Madeira (Funchal), Sail the Atlantic Ocean, Philipsburg, Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Dec 7, More...
14 Night - Jewels of the Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Valencia, Sail the Mediterranean Sea, Sardinia (Cagliari), Tunis (La Goulette), Palermo, Sicily, Naples, Rome (Civitavecchia)
2027 Sails: Dec 15, More...7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Dec 15, More...
7 Night - Amalfi Coast, Africa & Iberia
Starting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2027 Sails: Dec 15, Dec 29, More...14 Night - Jewels of the Mediterranean
Starting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2027 Sails: Dec 15, More...
14 Night - Ancient Mediterranean Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Heraklion), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2027 Sails: Dec 22, More...7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Heraklion), Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Dec 22, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Italy, France & Spain Cruise : Rome, Nice & BarcelonaStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Nice, Provence (Marseille), Barcelona
2027 Sails: Dec 4, More...
15 Night - Italy, France & Spain Combination Cruise : Rome, Barcelona & SevilleStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Nice, Provence (Marseille), Barcelona, Valencia, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon
2027 Sails: Dec 4, More...
14 Night - Cities of AntiquityStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Valletta, Sail the Ionian Sea, Corfu (Kerkyra), Katakolon (Olympia), Kalamata, Crete (Heraklion), Rhodes, Santorini (Thira), Athens (Piraeus)
2027 Sails: Dec 7, More...
20 Night - Atlantic & Mediterranean HorizonsStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Sail the Mediterranean Sea, Sail the Atlantic Ocean, Madeira (Funchal), Sail the Atlantic Ocean, Philipsburg, Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Dec 7, More...
14 Night - Jewels of the MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Valencia, Sail the Mediterranean Sea, Sardinia (Cagliari), Tunis (La Goulette), Palermo, Sicily, Naples, Rome (Civitavecchia)
2027 Sails: Dec 15, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Dec 15, More...
7 Night - Amalfi Coast, Africa & IberiaStarting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2027 Sails: Dec 15, Dec 29, More...
14 Night - Jewels of the MediterraneanStarting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2027 Sails: Dec 15, More...
14 Night - Ancient Mediterranean AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Heraklion), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2027 Sails: Dec 22, More...
7 Night - Journey to AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Heraklion), Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Dec 22, More...
