Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
9 Night - Italian Riviera, France & Spain
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Palma De Mallorca, Spain, Barcelona, Spain
2027 Sails: Jul 6, More...
21 Night - Adriatic & Mediterranean Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2027 Sails: Jul 10, More...14 Night - Italy, the Adriatic & Greece
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2027 Sails: Jul 10, More...
8 Night - Spotlight On Wine with Mercante
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Catania (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Koper, Venice (Fusina)
2027 Sails: Jul 11, More...
7 Night - Rome (Civitavecchia) / Venice
Starting in Rome (Civitavecchia), Amalfi, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2027 Sails: Jul 15, More...
10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Split, Croatia, Dubrovnik, Croatia, Montenegro, Corfu, Greece, Olympia (Katakolon), Greece, Sicily (Palermo), Italy, Naples, Italy, Rome (Civitavecchia), Italy
2027 Sails: Jul 16, More...
10 Night - Best of Italy & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Ravenna, Italy
2027 Sails: Jul 16, More...
10 Night - Italy, France & Spain Cruise : Florence, Marseille & Barcelona
Starting in Rome (Civitavecchia), Portoferraio (Elba), Florence / Pisa (Livorno), Porto Venere, Portofino (Santa Margherita), Monte Carlo, Provence (Marseille), Sete, Palamos, Barcelona
2027 Sails: Jul 17, More...
10 Night - Mountains & Mystery
Starting in Rome (Civitavecchia), Salerno, Catania (Sicily), Valletta, Taranto, Igoumenitsa, Bari, Kotor, Dubrovnik, Croatia, Zadar, Trieste
2027 Sails: Jul 17, More...
7 Night - Cruise Roundtrip from Rome (Civitavecchia)
Starting in Rome (Civitavecchia), Bonifacio, Corsica, Amalfi, Positano, Capri, Sorrento, Rome (Civitavecchia)
2027 Sails: Jul 18, Oct 3, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
9 Night - Italian Riviera, France & SpainStarting in Rome (Civitavecchia), Italy, Naples, Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Palma De Mallorca, Spain, Barcelona, Spain
2027 Sails: Jul 6, More...
21 Night - Adriatic & Mediterranean SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2027 Sails: Jul 10, More...
14 Night - Italy, the Adriatic & GreeceStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2027 Sails: Jul 10, More...
8 Night - Spotlight On Wine with MercanteStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Catania (Sicily), Cruising the Ionian Sea, Kotor, Dubrovnik, Croatia, Koper, Venice (Fusina)
2027 Sails: Jul 11, More...
7 Night - Rome (Civitavecchia) / VeniceStarting in Rome (Civitavecchia), Amalfi, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2027 Sails: Jul 15, More...
10 Night - Italy, Greece & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Split, Croatia, Dubrovnik, Croatia, Montenegro, Corfu, Greece, Olympia (Katakolon), Greece, Sicily (Palermo), Italy, Naples, Italy, Rome (Civitavecchia), Italy
2027 Sails: Jul 16, More...
10 Night - Best of Italy & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Ravenna, Italy
2027 Sails: Jul 16, More...
10 Night - Italy, France & Spain Cruise : Florence, Marseille & BarcelonaStarting in Rome (Civitavecchia), Portoferraio (Elba), Florence / Pisa (Livorno), Porto Venere, Portofino (Santa Margherita), Monte Carlo, Provence (Marseille), Sete, Palamos, Barcelona
2027 Sails: Jul 17, More...
Deal link -> Special
10 Night - Mountains & MysteryStarting in Rome (Civitavecchia), Salerno, Catania (Sicily), Valletta, Taranto, Igoumenitsa, Bari, Kotor, Dubrovnik, Croatia, Zadar, Trieste
2027 Sails: Jul 17, More...
7 Night - Cruise Roundtrip from Rome (Civitavecchia)Starting in Rome (Civitavecchia), Bonifacio, Corsica, Amalfi, Positano, Capri, Sorrento, Rome (Civitavecchia)
2027 Sails: Jul 18, Oct 3, More...
