Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
7 Night - Italy, Spain & French Riviera
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Santa Margherita, Italy, Cannes, France, Provence (Marseille), France, Valencia, Spain, Barcelona, Spain
2026 Sails: Sep 7, More...
10 Night - Coastal Mediterranean Gems
Starting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Cinque Terre (La Spezia), Villefranche, Provence (Marseille), Barcelona, Valencia, Alicante, Palma De Mallorca, Valletta
2026 Sails: Sep 10, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)
Starting in Rome (Civitavecchia), Sorrento, Taormina (Naxos), Sicily, Chania (Souda), Crete, Santorini, Milos, Athens (Piraeus)
2026 Sails: Sep 12, More...
12 Night - Artifacts & Antiquities
Starting in Rome (Civitavecchia), Amalfi / Positano, Naples / Pompeii, Cagliari (Sardinia), Trapani (Sicily), Valletta, Agios Nikolaos (Crete), Santorini, Ephesus (Kusadasi), Skiathos, Istanbul
2026 Sails: Sep 14, More...
7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona (Tarragona)
2026 Sails: Sep 15, More...
14 Night - Star Collector : Mediterranean Masterpieces of Italy & Northern Greece
Starting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece, Kusadasi, Kavala, Greece, Thessaloniki, Greece, Volos, Greece, Skopelos, Greece, Athens, Greece
2026 Sails: Sep 19, More...6 Night - Enchanting Greece & the Amalfi Coast
Starting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece
2026 Sails: Sep 19, More...9 Night - Enchanting Meteora, Greece, and Amalfi Coast Cruise Tour
Starting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece, Delphi, Athens, Greece
2026 Sails: Sep 19, More...
9 Night - Italian Riviera & France
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: Sep 22, More...
18 Night - Star Collector : Culture & Charms of Italy & Croatia
Starting in Rome, Syracuse, Italy, Gozo, Valletta, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Trogir, Croatia, Rovinj, Venice
2026 Sails: Sep 27, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Italy, Spain & French RivieraStarting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Santa Margherita, Italy, Cannes, France, Provence (Marseille), France, Valencia, Spain, Barcelona, Spain
2026 Sails: Sep 7, More...
10 Night - Coastal Mediterranean GemsStarting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Cinque Terre (La Spezia), Villefranche, Provence (Marseille), Barcelona, Valencia, Alicante, Palma De Mallorca, Valletta
2026 Sails: Sep 10, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)Starting in Rome (Civitavecchia), Sorrento, Taormina (Naxos), Sicily, Chania (Souda), Crete, Santorini, Milos, Athens (Piraeus)
2026 Sails: Sep 12, More...
12 Night - Artifacts & AntiquitiesStarting in Rome (Civitavecchia), Amalfi / Positano, Naples / Pompeii, Cagliari (Sardinia), Trapani (Sicily), Valletta, Agios Nikolaos (Crete), Santorini, Ephesus (Kusadasi), Skiathos, Istanbul
2026 Sails: Sep 14, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona (Tarragona)
2026 Sails: Sep 15, More...
14 Night - Star Collector : Mediterranean Masterpieces of Italy & Northern GreeceStarting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece, Kusadasi, Kavala, Greece, Thessaloniki, Greece, Volos, Greece, Skopelos, Greece, Athens, Greece
2026 Sails: Sep 19, More...
6 Night - Enchanting Greece & the Amalfi CoastStarting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece
2026 Sails: Sep 19, More...
9 Night - Enchanting Meteora, Greece, and Amalfi Coast Cruise TourStarting in Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece, Delphi, Athens, Greece
2026 Sails: Sep 19, More...
Deal link -> Special
9 Night - Italian Riviera & FranceStarting in Rome (Civitavecchia), Italy, Naples, Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: Sep 22, More...
18 Night - Star Collector : Culture & Charms of Italy & CroatiaStarting in Rome, Syracuse, Italy, Gozo, Valletta, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Trogir, Croatia, Rovinj, Venice
2026 Sails: Sep 27, More...
