Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 20, Aug 29, 2027: Jul 10, Aug 7, Oct 2, More...20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 20, 2027: Jul 10, Aug 7, More...
12 Night - Danube in Depth with Prague
Starting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jun 22, Jul 24, 2027: May 28, Jun 29, Jul 31, Sep 1, More...
11 Night - Cities of Light
Starting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Jun 24, More...
20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 28, 2027: Sep 21, More...17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 28, Oct 18, 2027: May 4, Sep 21, More...
23 Night - Jewels of Europe with Eastern Europe Explorer
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 28, Aug 9, Sep 6, More...
12 Night - Danube Explorer & Budapest with Prague
Starting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 7, Aug 8, More...
10 Night - Prague & Danube Explorer
Starting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 15, Jul 29, More...
12 Night - Magna On the Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Spitz, Vienna, Bratislava, Scenic Cruising, Budapest
2026 Sails: Jul 16, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 20, Aug 29, 2027: Jul 10, Aug 7, Oct 2, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 20, 2027: Jul 10, Aug 7, More...
12 Night - Danube in Depth with PragueStarting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jun 22, Jul 24, 2027: May 28, Jun 29, Jul 31, Sep 1, More...
11 Night - Cities of LightStarting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Jun 24, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 28, 2027: Sep 21, More...
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 28, Oct 18, 2027: May 4, Sep 21, More...
23 Night - Jewels of Europe with Eastern Europe ExplorerStarting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 28, Aug 9, Sep 6, More...
12 Night - Danube Explorer & Budapest with PragueStarting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 7, Aug 8, More...
10 Night - Prague & Danube ExplorerStarting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 15, Jul 29, More...
12 Night - Magna On the Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Spitz, Vienna, Bratislava, Scenic Cruising, Budapest
2026 Sails: Jul 16, More...
