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Prague Cruise Departures

Cruises that depart from Europe: Czech Republic: Prague

Cruises that visit Prague

See all River Cruises that depart from Prague

Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Prague
Shore Excursions

Emerald Cruises, Emerald Luna
Emerald Luna17 Night - Prague & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 2, More...
Amadeus River Tours, MS Amadeus Nova Tours
MS Amadeus Nova Tours10 Night - Prague Adventure and Classical Danube Cruise
Starting in Prague, Passau, Linz, Emmersdorf, Vienna, Esztergom, Budapest
2026 Sails: Oct 1, More...
Emerald Cruises, Emerald Luna
Emerald Luna24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Oct 7, More...
AmaWaterways Tours, AmaReina Tours
AmaReina Tours10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 25, 2027: Oct 31, More...
AmaWaterways Tours, AmaMora Tours
AmaMora Tours10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 28, 2027: Oct 27, Dec 22, More...
AmaWaterways Tours, AmaSofia Tours
AmaSofia Tours10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 29, More...
AmaWaterways Tours, AmaBella Tours
AmaBella Tours10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Waca, Weissenkirchen, Vienna, Budapest
2026 Sails: Oct 30, More...
Scenic Luxury, Scenic Amber
Scenic Amber20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, More...
AmaWaterways Tours, AmaSonata Tours
AmaSonata Tours10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Nov 1, 2027: Nov 7, More...
AmaWaterways Tours, AmaMagna Tours
AmaMagna Tours12 Night - Magna On the Danube (Wine Cruise) with Prague Pre-Cruise and Budapest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Springdale, Vienna, Prudhoe Bay / Deadhorse, Budapest
2026 Sails: Nov 5, 2027: Nov 4, More...

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Prague Cruise Departures