Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
21 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Brasov, Bucharest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Prudhoe Bay / Deadhorse, Vidin, Rousse, Giurgiu, Gordon, Bucharest
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Budapest
2026 Sails: Aug 7, 2027: Aug 6, More...
17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 7, Oct 30, More...
20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Aug 9, More...17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 9, More...20 Night - Jewels of Europe with Prague and London
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / London, London
2026 Sails: Aug 9, More...
18 Night - Portraits of Eastern Europe
Starting in Prague, Prague, Transfer to Regensburg, Regensburg, Passau, Linz, Durnstein, Vienna, Budapest, Batina (Osijek), Vukovar, Belgrade, Golubac, Cruising the Iron Gates, Vidin, Ruse, Giurgiu, Transfer to Bucharest, Bucharest
2026 Sails: Aug 14, More...
16 Night - Danube in Depth with Prague, Ljubljana & Zagreb
Starting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest, Budapest / Ljubljana, Ljubljana, Ljubljana / Zagreb, Zagreb / Plitvice National Park / Zagreb, Zagreb
2026 Sails: Aug 25, More...
13 Night - Europe's Rivers & Castles with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Labuha, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 30, Oct 25, 2027: Mar 28, May 9, Aug 29, Oct 10, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Sep 1, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
21 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Brasov, Bucharest Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Prudhoe Bay / Deadhorse, Vidin, Rousse, Giurgiu, Gordon, Bucharest
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Budapest
2026 Sails: Aug 7, 2027: Aug 6, More...
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 7, Oct 30, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Aug 9, More...
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 9, More...
20 Night - Jewels of Europe with Prague and LondonStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / London, London
2026 Sails: Aug 9, More...
18 Night - Portraits of Eastern EuropeStarting in Prague, Prague, Transfer to Regensburg, Regensburg, Passau, Linz, Durnstein, Vienna, Budapest, Batina (Osijek), Vukovar, Belgrade, Golubac, Cruising the Iron Gates, Vidin, Ruse, Giurgiu, Transfer to Bucharest, Bucharest
2026 Sails: Aug 14, More...
16 Night - Danube in Depth with Prague, Ljubljana & ZagrebStarting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest, Budapest / Ljubljana, Ljubljana, Ljubljana / Zagreb, Zagreb / Plitvice National Park / Zagreb, Zagreb
2026 Sails: Aug 25, More...
13 Night - Europe's Rivers & Castles with Prague Pre-Cruise and Paris Post-CruiseStarting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Labuha, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 30, Oct 25, 2027: Mar 28, May 9, Aug 29, Oct 10, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Sep 1, More...
