Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
9 Night - Vineyards & Palaces Along the Danube with Prague
Starting in Arrive in Prague, Transfer to Hotel, Prague, Prague, Transfer to Nuremberg, Nuremberg, Regensburg, Straubing, Vilshofen, Engelhartszell, Passau, Vilshofen, Grein, Spitz, Vienna
2026 Sails: Sep 4, Sep 18, More...16 Night - Danube Grandeur & Prague
Starting in Arrive in Prague, Transfer to Hotel, Prague, Prague, Transfer to Nuremberg, Nuremberg, Regensburg, Straubing, Vilshofen, Engelhartszell, Passau, Vilshofen, Grein, Spitz, Vienna, Bratislava, Budapest, Batina, Ilok, Novi Sad, Belgrade
2026 Sails: Sep 18, More...
10 Night - Prague Adventure and Classical Danube Cruise
Starting in Prague, Passau, Linz, Emmersdorf, Vienna, Esztergom, Budapest
2026 Sails: Oct 1, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Oct 5, More...
10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 20, More...
10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 25, More...
10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 28, More...
10 Night - Romantic Danube (Modified) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 29, More...
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Waca, Weissenkirchen, Vienna, Budapest
2026 Sails: Oct 30, More...
20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
9 Night - Vineyards & Palaces Along the Danube with PragueStarting in Arrive in Prague, Transfer to Hotel, Prague, Prague, Transfer to Nuremberg, Nuremberg, Regensburg, Straubing, Vilshofen, Engelhartszell, Passau, Vilshofen, Grein, Spitz, Vienna
2026 Sails: Sep 4, Sep 18, More...
16 Night - Danube Grandeur & PragueStarting in Arrive in Prague, Transfer to Hotel, Prague, Prague, Transfer to Nuremberg, Nuremberg, Regensburg, Straubing, Vilshofen, Engelhartszell, Passau, Vilshofen, Grein, Spitz, Vienna, Bratislava, Budapest, Batina, Ilok, Novi Sad, Belgrade
2026 Sails: Sep 18, More...
10 Night - Prague Adventure and Classical Danube CruiseStarting in Prague, Passau, Linz, Emmersdorf, Vienna, Esztergom, Budapest
2026 Sails: Oct 1, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Oct 5, More...
10 Night - Classic Prague & Danube DelightsStarting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 20, More...
10 Night - Romantic Danube (Modified) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 25, More...
10 Night - Romantic Danube (Modified) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 28, More...
10 Night - Romantic Danube (Modified) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Prudhoe Bay / Deadhorse, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Oct 29, More...
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Waca, Weissenkirchen, Vienna, Budapest
2026 Sails: Oct 30, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, More...
