Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
10 Night - Gems of the Danube with Prague
Starting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jul 25, 2027: May 8, May 22, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Aug 1, More...
10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Aug 4, Sep 3, Sep 17, Oct 29, 2027: Mar 26, Oct 10, More...
20 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Istanbul Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...21 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Brasov, Bucharest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Bran, Brasov, Bucharest
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Scenic Cruising, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Aug 7, Dec 25, 2027: Jul 9, Aug 6, More...
17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 7, 2027: May 7, Aug 27, Oct 22, More...
20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Aug 9, Sep 6, 2027: Apr 20, Oct 5, More...17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 9, Sep 6, 2027: Apr 20, Jun 15, Aug 10, Sep 7, Oct 5, More...12 Night - Danube Explorer & Budapest with Prague
Starting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Aug 18, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Gems of the Danube with PragueStarting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jul 25, 2027: May 8, May 22, More...
11 Night - Illuminations On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Regensburg, Germany / Vilshofen (Embarkation), Passau / Schlogen Oxbow, Linz, Austria, Melk / Wachau Valley, Vienna, Austria, Vienna, Bratislava, Slovakia, Esztergom, Hungary, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Aug 1, More...
10 Night - Classic Prague & Danube DelightsStarting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Aug 4, Sep 3, Sep 17, Oct 29, 2027: Mar 26, Oct 10, More...
20 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Istanbul Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...
21 Night - Grand Danube (Smithsonian Journeys) with Prague Pre-Cruise and Brasov, Bucharest Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Bran, Brasov, Bucharest
2026 Sails: Aug 7, 2027: May 14, Jun 11, Sep 3, Oct 1, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Scenic Cruising, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Aug 7, Dec 25, 2027: Jul 9, Aug 6, More...
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 7, 2027: May 7, Aug 27, Oct 22, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Aug 9, Sep 6, 2027: Apr 20, Oct 5, More...
17 Night - Jewels of Europe with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 9, Sep 6, 2027: Apr 20, Jun 15, Aug 10, Sep 7, Oct 5, More...
12 Night - Danube Explorer & Budapest with PragueStarting in Prague, Prague / Passau, Passau, Linz / Cesky Krumlov, Melk / Weissenkirchen, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Aug 18, More...
