Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Jul 24, Oct 16, 2027: Apr 2, Jul 23, Aug 20, More...20 Night - Grand Danube Cruise (Wine Cruise) with Prague Pre-Cruise and Istanbul Post-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest, Mohacs, Vukovar, Belgrade, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Jul 24, More...21 Night - Grand Danube Cruise (Wine Cruise) with Prague Pre-Cruise and Brasov, Bucharest Post-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest, Mohacs, Vukovar, Belgrade, Vidin, Rousse, Giurgiu, Bucharest
2026 Sails: Jul 24, More...
12 Night - Danube in Depth with Prague
Starting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 24, More...
10 Night - Gems of the Danube with Prague
Starting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jul 25, 2027: May 8, May 22, Jul 3, More...
10 Night - Romantic Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Jul 26, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, 2027: Mar 14, Mar 28, Apr 11, Apr 25, Jun 20, Jul 18, Aug 1, Aug 29, Sep 12, Oct 10, More...
24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jul 29, Oct 7, More...
12 Night - Magna On the Danube with Prague Pre-Cruise and Budapest Post-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Grein, Melk, Spitz, Vienna, Bratislava, Budapest
2026 Sails: Jul 30, Aug 27, Sep 10, Sep 24, 2027: May 6, Jun 3, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, More...
13 Night - Europe's Rivers & Castles (Wine Cruise) with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 2, 2027: Mar 21, May 2, Aug 8, Sep 19, More...
10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Aug 4, Sep 17, Oct 29, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Jul 24, Oct 16, 2027: Apr 2, Jul 23, Aug 20, More...
20 Night - Grand Danube Cruise (Wine Cruise) with Prague Pre-Cruise and Istanbul Post-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest, Mohacs, Vukovar, Belgrade, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Jul 24, More...
21 Night - Grand Danube Cruise (Wine Cruise) with Prague Pre-Cruise and Brasov, Bucharest Post-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest, Mohacs, Vukovar, Belgrade, Vidin, Rousse, Giurgiu, Bucharest
2026 Sails: Jul 24, More...
12 Night - Danube in Depth with PragueStarting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Jul 24, More...
10 Night - Gems of the Danube with PragueStarting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jul 25, 2027: May 8, May 22, Jul 3, More...
10 Night - Romantic Danube with Prague Pre-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Jul 26, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, 2027: Mar 14, Mar 28, Apr 11, Apr 25, Jun 20, Jul 18, Aug 1, Aug 29, Sep 12, Oct 10, More...
24 Night - Eastern European Escapade & Splendours of EuropeStarting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jul 29, Oct 7, More...
12 Night - Magna On the Danube with Prague Pre-Cruise and Budapest Post-CruiseStarting in Prague, Regensburg, Villany, Passau, Linz, Grein, Melk, Spitz, Vienna, Bratislava, Budapest
2026 Sails: Jul 30, Aug 27, Sep 10, Sep 24, 2027: May 6, Jun 3, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, More...
13 Night - Europe's Rivers & Castles (Wine Cruise) with Prague Pre-Cruise and Paris Post-CruiseStarting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 2, 2027: Mar 21, May 2, Aug 8, Sep 19, More...
10 Night - Classic Prague & Danube DelightsStarting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Aug 4, Sep 17, Oct 29, More...
