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Prague Cruise Departures

Cruises that depart from Europe: Czech Republic: Prague

Cruises that visit Prague

See all River Cruises that depart from Prague

Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper Cruises20 Night - Christmas Markets with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, 2027: Nov 20, More...
AmaWaterways Cruise Tours, AmaReina Cruise Tours
AmaReina Cruise Tours10 Night - Iconic Christmas Markets with Prague Pre-Cruise
Starting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 22, 2027: Dec 12, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises17 Night - Christmas Markets with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 22, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises20 Night - Christmas Markets with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 22, More...
AmaWaterways Cruise Tours, AmaSofia Cruise Tours
AmaSofia Cruise Tours10 Night - Christmas Markets On the Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Nov 26, Dec 10, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises8 Night - Prague to Budapest & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises6 Night - Prague & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...
AmaWaterways Cruise Tours, AmaBella Cruise Tours
AmaBella Cruise Tours10 Night - Christmas Markets On the Danube with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Budapest
2026 Sails: Nov 27, More...
Avalon Waterways Cruise Tours, Avalon Illumination Cruise Tours
Avalon Illumination Cruises9 Night - Christmastime On the Legendary Danube with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Nov 27, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruises8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Nov 27, Dec 9, More...

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Prague Cruise Departures