Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 20, 2027: May 12, May 26, Jun 9, Aug 8, Aug 22, Sep 5, More...
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Wachau Valley, Weissenkirchen, Krems, Vienna, Budapest
2026 Sails: Oct 30, More...
20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, 2027: May 7, More...
20 Night - Grand Danube Cruise with Prague Pre-Cruise and Istanbul Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Ilok, Novi Sad, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Nov 5, More...21 Night - Grand Danube Cruise with Prague Pre-Cruise and Brasov, Bucharest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Ilok, Novi Sad, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Sinaia, Brasov, Bucharest
2026 Sails: Nov 5, More...12 Night - Magna On the Danube (Wine Cruise) with Prague Pre-Cruise and Budapest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Spitz, Vienna, Scenic Cruising, Budapest
2026 Sails: Nov 5, 2027: Nov 4, More...
10 Night - Romantic Danube (Festive Delights) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Nov 18, More...
20 Night - Prague to Paris & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, 2027: Nov 19, More...17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 19, More...
17 Night - Christmas Markets with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 20, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Classic Prague & Danube DelightsStarting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 20, 2027: May 12, May 26, Jun 9, Aug 8, Aug 22, Sep 5, More...
10 Night - Romantic Danube (Wine Cruise) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Wachau Valley, Weissenkirchen, Krems, Vienna, Budapest
2026 Sails: Oct 30, More...
20 Night - Jewels of Europe with Prague & ParisStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, 2027: May 7, More...
20 Night - Grand Danube Cruise with Prague Pre-Cruise and Istanbul Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Ilok, Novi Sad, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Istanbul
2026 Sails: Nov 5, More...
21 Night - Grand Danube Cruise with Prague Pre-Cruise and Brasov, Bucharest Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest, Mohacs, Vukovar, Ilok, Novi Sad, Belgrade, Iron Gates, Scenic Cruising, Vidin, Rousse, Giurgiu, Sinaia, Brasov, Bucharest
2026 Sails: Nov 5, More...
12 Night - Magna On the Danube (Wine Cruise) with Prague Pre-Cruise and Budapest Post-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Spitz, Vienna, Scenic Cruising, Budapest
2026 Sails: Nov 5, 2027: Nov 4, More...
10 Night - Romantic Danube (Festive Delights) with Prague Pre-CruiseStarting in Prague, Regensburg, Vilshofen, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Nov 18, More...
20 Night - Prague to Paris & Christmas Markets of EuropeStarting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, 2027: Nov 19, More...
17 Night - Prague & Christmas Markets of EuropeStarting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 19, More...
17 Night - Christmas Markets with PragueStarting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 20, More...
