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Prague Cruise Departures

Cruises that depart from Europe: Czech Republic: Prague

Cruises that visit Prague

See all River Cruises that depart from Prague

Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Prague
Shore Excursions

Scenic Luxury, Scenic Opal
Scenic Opal10 Night - Gems of the Danube with Prague
Starting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Dec 12, 2027: Sep 25, Oct 9, More...
Scenic Luxury, Scenic Pearl
Scenic Pearl10 Night - Danube Christmas Markets with Prague
Starting in Prague, Prague / Regensburg, Regensburg, Passau / Schlogen, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Dec 13, More...
Scenic Luxury, Scenic Opal
Scenic Opal17 Night - Christmas & New Year with Prague
Starting in Prague, Prague / Budapest, Budapest, Cruising Day, Vienna, Durnstein / Melk, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Cruising Day, Rudesheim, Cologne, Amsterdam
2026 Sails: Dec 19, More...
Scenic Luxury, Scenic Opal
Scenic Opal20 Night - Christmas & New Year with Paris & Prague
Starting in Prague, Prague / Budapest, Budapest, Cruising Day, Vienna, Durnstein / Melk, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Cruising Day, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Dec 19, More...
AmaWaterways Tours, AmaMora Tours
AmaMora Tours10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Waca, Weissenkirchen, Vienna, Budapest
2027 Sails: Feb 17, Mar 3, Mar 31, Jul 21, Aug 4, Nov 10, More...
AmaWaterways Tours, AmaMagna Tours
AmaMagna Tours12 Night - Magna On the Danube (Wine Cruise) with Prague Pre-Cruise and Budapest Post-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Grein, Melk, Springdale, Vienna, Budapest
2027 Sails: Mar 11, More...
AmaWaterways Tours, AmaBella Tours
AmaBella Tours10 Night - Romantic Danube (Wine Cruise) with Prague Pre-Cruise
Starting in Prague, Regensburg, Vilshofen, Passau, Linz, Waca, Weissenkirchen, Vienna, Budapest
2027 Sails: Mar 19, Apr 16, Oct 29, More...
Scenic Luxury, Scenic Opal
Scenic Opal17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2027 Sails: Mar 20, More...
Emerald Cruises, Emerald Sky
Emerald Sky10 Night - Classic Prague & Danube Delights
Starting in Prague, Prague / Regensburg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2027 Sails: Mar 26, More...
Uniworld Tours, S.S. Beatrice Tours
S.S. Beatrice Tours9 Night - Delightful Danube & Prague
Starting in Prague, Prague, Transfer to Regensburg, Regensburg, Passau, Melk, Vienna, Vienna, Vienna / Bratislava, Budapest
2027 Sails: Mar 26, Apr 9, May 7, May 21, Jun 18, Jul 2, Jul 30, Aug 13, Sep 10, Sep 24, Oct 22, Nov 5, More...

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Prague Cruise Departures