Prague Cruise Departures
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
10 Night - Classic Prague & Christmas Markets On the Danube
Starting in Prague, Prague / Passau, Passau, Linz, Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Nov 28, Dec 12, More...
10 Night - Iconic Christmas Markets with Prague Pre-Cruise
Starting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 29, Dec 13, 2027: Dec 5, More...
11 Night - Christmastime from Nuremberg to Basel with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Nov 29, More...7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...
20 Night - Prague to Paris & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 29, More...17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 29, 2027: Dec 3, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 2, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 3, Dec 15, More...
9 Night - Christmastime On the Legendary Danube with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Dec 6, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 6, More...
Cruises that depart from Europe: Czech Republic: Prague
Cruises that visit Prague
See all River Cruises that depart from Prague
Click on a cruise ship itinerary sailing from Prague (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Prague), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Classic Prague & Christmas Markets On the DanubeStarting in Prague, Prague / Passau, Passau, Linz, Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Nov 28, Dec 12, More...
10 Night - Iconic Christmas Markets with Prague Pre-CruiseStarting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 29, Dec 13, 2027: Dec 5, More...
11 Night - Christmastime from Nuremberg to Basel with in PragueStarting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Nov 29, More...
7 Night - Christmastime in the Heart of Germany with in PragueStarting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...
20 Night - Prague to Paris & Christmas Markets of EuropeStarting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 29, More...
17 Night - Prague & Christmas Markets of EuropeStarting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 29, 2027: Dec 3, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 2, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 3, Dec 15, More...
9 Night - Christmastime On the Legendary Danube with in PragueStarting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Dec 6, More...
8 Night - Christmastime On the Danube with in Prague (Eastbound)Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 6, More...
