Palermo Cruise Departures
Cruises that depart from Mediterranean: Italy: Palermo
Cruises that visit Palermo
4 Night - Western Mediterranean from Palermo
Starting in Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 16, More...
7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Ibiza, Spain, Palermo (Sicily)
2026 Sails: Sep 24, More...7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Ibiza, Spain, Palermo (Sicily)
2026 Sails: Oct 1, More...7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 8, Oct 15, More...
26 Night - Msc Grand Voyages
Starting in Palermo (Monreale), Italy, Naples (Pompeii), Italy, Livorno (Florence), Italy, Marseille (Provence), France, Barcelona, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Funchal (Madeira Islands), Portugal, Ponta Delgada (Azores), Portugal, Boston, New York City (Brooklyn), New York, Miami, Florida
2026 Sails: Oct 16, More...7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 22, Oct 29, More...
7 Night - Mediterranean
Starting in Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy
2026 Sails: Oct 28, Nov 4, Nov 11, Nov 18, Nov 25, Dec 2, Dec 9, Dec 16, Dec 23, Dec 30, 2027: Jan 6, Jan 13, Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, Mar 10, Mar 17, Mar 24, Mar 31, Nov 3, More...
21 Night - Msc Grand Voyages
Starting in Palermo (Monreale), Italy, La Valletta, Malta, Barcelona, Spain, Gibraltar, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Maceio, Brazil, Salvador, Brazil, Rio De Janeiro, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 12, More...
7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, La Goulette, Tunisia, Tunis Gulf, Palermo (Sicily)
2026 Sails: Nov 26, Dec 3, Dec 10, Dec 17, Dec 24, Dec 31, 2027: Jan 7, More...7 Night - Western Mediterranean Roundtrip from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, La Goulette, Tunisia, Tunis Gulf, Palermo (Sicily)
2027 Sails: Jan 14, Jan 21, More...
Cruises that depart from Mediterranean: Italy: Palermo
Cruises that visit Palermo
Click on a cruise ship itinerary sailing from Palermo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Palermo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
4 Night - Western Mediterranean from PalermoStarting in Palermo, Napoli, Civitavecchia (Rome), Ajaccio, Savona
2026 Sails: Sep 16, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Ibiza, Spain, Palermo (Sicily)
2026 Sails: Sep 24, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Ibiza, Spain, Palermo (Sicily)
2026 Sails: Oct 1, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 8, Oct 15, More...
26 Night - Msc Grand VoyagesStarting in Palermo (Monreale), Italy, Naples (Pompeii), Italy, Livorno (Florence), Italy, Marseille (Provence), France, Barcelona, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Funchal (Madeira Islands), Portugal, Ponta Delgada (Azores), Portugal, Boston, New York City (Brooklyn), New York, Miami, Florida
2026 Sails: Oct 16, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, Cagliari, Italy, Palermo (Sicily)
2026 Sails: Oct 22, Oct 29, More...
7 Night - MediterraneanStarting in Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy
2026 Sails: Oct 28, Nov 4, Nov 11, Nov 18, Nov 25, Dec 2, Dec 9, Dec 16, Dec 23, Dec 30, 2027: Jan 6, Jan 13, Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, Mar 10, Mar 17, Mar 24, Mar 31, Nov 3, More...
21 Night - Msc Grand VoyagesStarting in Palermo (Monreale), Italy, La Valletta, Malta, Barcelona, Spain, Gibraltar, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Maceio, Brazil, Salvador, Brazil, Rio De Janeiro, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 12, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, La Goulette, Tunisia, Tunis Gulf, Palermo (Sicily)
2026 Sails: Nov 26, Dec 3, Dec 10, Dec 17, Dec 24, Dec 31, 2027: Jan 7, More...
7 Night - Western Mediterranean Roundtrip from PalermoStarting in Palermo (Sicily), Civitavecchia / Rome, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, La Goulette, Tunisia, Tunis Gulf, Palermo (Sicily)
2027 Sails: Jan 14, Jan 21, More...
