Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

PONANT, Le Bougainville

7 Night - Natural Wonders and Cultural Jewels of Dalmatia
Starting in Venice, Rovinj, Zadar, Primosten, Split, Hvar, Korcula, Mljet, Tivat, Dubrovnik, Croatia
2026 Sails: Aug 20, More...

Royal Caribbean, Legend of the Seas

7 Night - Western Mediterranean Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 20, More...

Star Clippers, Star Clipper

16 Night - Grand Voyage : Venice to Rome
Starting in Venice, Italy, Mali Losinj, Croatia, Sibenik, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Otranto, Italy, Taormina, Sicily, Italy, Lipari / Aeolian Islands, Italy, Amalfi, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy, Amalfi, Italy, Sorrento, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy
2026 Sails: Aug 20, More...

Uniworld Tours, S.S. La Venezia Tours

19 Night - Cruise & Rail : Slovenia, Venice, Istanbul & the Balkans
Starting in Ljubljana, Ljubljana (Lake Bled), Ljubljana (Karst), Transfer to Venice, Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Pula, Rijeka, Sarajevo, Mostar, Belgrade, Sofia, Plovdiv, Istanbul
2026 Sails: Aug 20, Sep 24, 2027: Apr 29, More...

Atlas Ocean Voyages, World Traveller

6 Night - Valletta to Athens
Starting in Valletta, Nafplion (Mycenae / Epidaurus), Chania (Crete), Greece, Agios Nikolaos (Crete), Milos, Piraeus (Athens)
2026 Sails: Aug 21, More...

Celebrity Cruises, Celebrity Constellation

10 Night - Best of Italy & Croatia Cruise
Starting in Ravenna, Italy, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Sicily (Messina), Italy, Amalfi Coast (Salerno), Italy, Portofino, Italy, Florence / Pisa (Livorno), Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 21, More...

Ritz-Carlton, Ilma

7 Night - Monte Carlo / Monte Carlo
Starting in Monte Carlo, Saint-Tropez, Calvi, Corsica, Ajaccio, Corsica, Alghero, Sardinia, Bonifacio, Corsica, Portofino, Monte Carlo
2026 Sails: Aug 21, More...

Costa Cruise Lines, Costa Deliziosa

14 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Corfu, Argostoli (Cephalonia), Dubrovnik, Croatia, Kotor, Zadar, Marghera (Venice), Bari, Thira (Santorini), Mykonos, Katakolon (Olympia), Marghera (Venice)
2026 Sails: Aug 22, More...

Holland America, Oosterdam

7 Night - Mediterranean Splendor : Sicily
Starting in Piraeus (Athens), Greece, Kotor, Montenegro, Scenic cruising Bay of Kotor, Kerkira, (Corfu), Greece, Messina, Italy, Cruising Strait of Messina, Evening cruising Stromboli Volcano, Salerno, Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 22, More...

Oceania Cruises, Oceania Allura

14 Night - Moroccan & Spanish Delights
Starting in Valletta, Tunis (La Goulette), Cartagena ES, Malaga, Funchal (Madeira), Santa Cruz de La Palma, Santa Cruz de Tenerife, Arrecife (Lanzarote), Agadir, Casablanca, Seville (Cadiz), Barcelona
2026 Sails: Aug 22, More...

<= Back

More =>

Mediterranean Cruise Departures