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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Royal Caribbean, Explorer of the Seas
Explorer of the Seas7 Night - Greece & Croatia Cruise
Starting in Ravenna, Italy, Dubrovnik, Croatia, Athens (Piraeus), Greece, Santorini, Greece, Zadar, Croatia, Ravenna, Italy
2026 Sails: Aug 15, More...
Silversea, Silver Ray
Silver Ray9 Night - Monte Carlo to Barcelona
Starting in Monte Carlo, Saint Tropez, Cartagena ES, Spain, Valencia, Palma De Mallorca, Palamos, Marseille, Barcelona
2026 Sails: Aug 15, More...
Atlas Ocean Voyages, World Traveller
World Traveller11 Night - Monte Carlo to Athens
Starting in Monte Carlo, Trapani (Sicily), La Goulette, Porto Empedocle (Sicily), Valletta, Nafplion (Mycenae / Epidaurus), Chania (Crete), Greece, Agios Nikolaos (Crete), Milos, Piraeus (Athens)
2026 Sails: Aug 16, More...
Atlas Ocean Voyages, World Traveller
World Traveller5 Night - Monte Carlo to Valletta
Starting in Monte Carlo, Trapani (Sicily), La Goulette, Porto Empedocle (Sicily), Valletta
2026 Sails: Aug 16, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Savona
Starting in Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona
2026 Sails: Aug 16, Aug 23, Aug 30, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem7 Night - Europe - Adriatic & Greece - Venice
Starting in Venice (Ravenna), Italy, Split, Croatia, Zadar, Croatia, Kotor, Montenegro, Corfu, Greece, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Aug 16, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl7 Night - Europe
Starting in Piraeus / Athens, Greece, Santorini Island, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Kotor, Montenegro, Dubrovnik, Croatia, Koper, Slovenia, Venice (Ravenna), Italy
2026 Sails: Aug 16, More...
Silversea, Silver Nova
Silver Nova7 Night - Athens to Athens
Starting in Athens (Piraeus), Gythion, Katakolon (Olympia), Santorini, Souda Bay (Crete), Bodrum, Patmos, Athens (Piraeus)
2026 Sails: Aug 16, More...
Celebrity Cruises, Celebrity Ascent
Celebrity Ascent11 Night - Greece, Turkey & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Santorini, Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 17, Oct 19, 2027: May 24, Aug 16, Sep 27, More...
Oceania Cruises, Oceania Regatta
Oceania Regatta10 Night - Bridge to the Bosphorus
Starting in Dubrovnik, Croatia, Kotor, Igoumenitsa, Katakolon, Santorini, Mykonos, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...

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Mediterranean Cruise Departures