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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

AmaWaterways Tours, AmaBella Tours
AmaBella Tours20 Night - Grand Danube Cruise with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Grein, Linz, Passau, Villany, Regensburg, Prague
2026 Sails: Jul 24, Aug 21, Nov 13, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Genova
Starting in Genoa (Portofino), Marseille, Barcelona, Cagliari, Napoli, Civitavecchia (Rome), Genoa (Portofino)
2026 Sails: Jul 24, Jul 31, Aug 7, More...
Ritz-Carlton, Ilma
Ilma7 Night - Rome (Civitavecchia) / Rome (Civitavecchia)
Starting in Rome (Civitavecchia), Valletta, Trapani, Palermo, Sicily, Amalfi, Sorrento, Rome (Civitavecchia)
2026 Sails: Jul 24, More...
Windstar, Wind Surf
Wind Surf8 Night - Classic Italy & Dalmatian Coast
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome
2026 Sails: Jul 24, Aug 18, More...
Windstar, Wind Surf
Wind Surf16 Night - Star Collector : Southern Italian Enchantment & Balkan Beaches
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice
2026 Sails: Jul 24, More...
Azamara Cruises, Azamara Onward
Azamara Onward8 Night - Greece Intensive Cruise : Syros, Patmos & Santorini
Starting in Athens (Piraeus), Syros, Patmos, Rhodes, Marmaris, Agios Nikolaos, (Crete), Santorini, Monemvasia, Athens (Piraeus)
2026 Sails: Jul 25, More...
Celestyal Cruises, Celestyal Journey
Celestyal Journey14 Night - Mediterranean Icons (East to West)
Starting in Piraeus, Athens, Kusadasi, Rhodes, Agios Nikolaos, Crete, Santorini, Mykonos, Milos, Piraeus, Athens, Cephalonia, Dubrovnik, Croatia, Kotor, Bari, Kerkira (Corfu), Katakolon, Piraeus, Athens
2026 Sails: Jul 25, Aug 8, Aug 22, Oct 10, Oct 24, 2027: Mar 13, Mar 27, Apr 10, Apr 24, Jul 24, Aug 7, Aug 21, Oct 9, Oct 23, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa7 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Corfu, Argostoli (Cephalonia), Dubrovnik, Croatia, Kotor, Zadar, Marghera (Venice)
2026 Sails: Jul 25, Aug 22, More...
PONANT, Le Ponant
Le Ponant7 Night - Croatia
Starting in Dubrovnik, Croatia, Mljet, Komiza, Vis Island, Vis Island, Stari Grad, Hvar Island, Korcula, Dubrovnik, Croatia, Sipan Island, Kotor, Dubrovnik, Croatia
2026 Sails: Jul 25, More...
Royal Caribbean, Legend of the Seas
Legend of the Seas8 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Naples, Italy, Palma De Mallorca, Spain, Malaga, Spain, Barcelona, Spain
2026 Sails: Jul 25, More...

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Mediterranean Cruise Departures