Madrid Cruise Departures
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, More...
21 Night - Highlights of Spain - Tour 2D
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
14 Night - Next Stop Madrid : Spanish Treasures Cruise Tour
Starting in Madrid, Spain, Barcelona, Tarragona, Spain, Palma De Mallorca, Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 26, More...
12 Night - Spanish Symphony & Madrid Medley Cruise Tour
Starting in Madrid, Spain, Barcelona, Palma De Mallorca, Cartagena ES, Almeria, Spain, Malaga, Gibraltar, Cadiz, Lisbon
2026 Sails: Oct 26, More...
14 Night - Next Stop Madrid : Spanish Treasures Cruise Tour
Starting in Madrid, Spain, Barcelona, Tarragona, Spain, Palma De Mallorca, Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 27, More...
13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Nov 4, More...13 Night - Flavors of Portugal & Spain (Taste of Christmas) with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Bermuda, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Nov 18, Dec 2, 2027: Nov 17, Dec 1, Dec 15, More...
13 Night - Madrid & Southern Spain Winter Escapes Cruise Tour
Starting in Madrid, Spain, Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2027 Sails: Jan 2, Feb 10, More...13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2027 Sails: Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, More...
10 Night - Madrid & Secrets of the Douro
Starting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua / Porto, Porto
2027 Sails: Apr 7, May 19, Jun 30, More...
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
Click on a cruise ship itinerary sailing from Madrid (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Madrid), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-CruiseStarting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, More...
21 Night - Highlights of Spain - Tour 2DStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
14 Night - Next Stop Madrid : Spanish Treasures Cruise TourStarting in Madrid, Spain, Barcelona, Tarragona, Spain, Palma De Mallorca, Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 26, More...
12 Night - Spanish Symphony & Madrid Medley Cruise TourStarting in Madrid, Spain, Barcelona, Palma De Mallorca, Cartagena ES, Almeria, Spain, Malaga, Gibraltar, Cadiz, Lisbon
2026 Sails: Oct 26, More...
14 Night - Next Stop Madrid : Spanish Treasures Cruise TourStarting in Madrid, Spain, Barcelona, Tarragona, Spain, Palma De Mallorca, Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 27, More...
13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-CruiseStarting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Nov 4, More...
13 Night - Flavors of Portugal & Spain (Taste of Christmas) with Madrid Pre-Cruise and Lisbon Post-CruiseStarting in Madrid, Salamanca, Vega de Terron, Bermuda, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Nov 18, Dec 2, 2027: Nov 17, Dec 1, Dec 15, More...
13 Night - Madrid & Southern Spain Winter Escapes Cruise TourStarting in Madrid, Spain, Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2027 Sails: Jan 2, Feb 10, More...
13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-CruiseStarting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2027 Sails: Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, More...
10 Night - Madrid & Secrets of the DouroStarting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua / Porto, Porto
2027 Sails: Apr 7, May 19, Jun 30, More...
