Los Angeles Cruise Departures
Cruises that depart from North America: United States: California: Los Angeles
Cruises that visit Los Angeles
101 Night - Msc World Cruise
Starting in Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Feb 6, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Feb 9, Sep 20, Dec 28, 2027: Mar 2, Apr 3, More...
6 Night - Cabo & Ensenada Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
16 Night - Hawaiian Islands
Starting in Los Angeles, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 20, More...54 Night - South Pacific, Australia & New Zealand
Starting in Los Angeles, California, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Raiatea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Tauranga, New Zealand, Bay of Islands, New Zealand, Hobart, Australia, Sydney AU, Brisbane, Australia, Noumea, New Caledonia, Mystery Island, Vanuatu, Suva, Fiji, Dravuni Island, Fiji, Apia, Western Samoa, Cross International Date Line, Hilo, Hawaii, Kona, Hawaii, Los Angeles, California
2026 Sails: Mar 13, More...4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Mar 16, More...
7 Night - Mexican Riviera
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 28, More...7 Night - Classic California Coast
Starting in Los Angeles, California, San Francisco, California, Santa Barbara, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Apr 4, More...
25 Night - Los Angeles to Southampton
Starting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Apr 5, More...14 Night - Los Angeles to Miami
Starting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Apr 5, More...
Cruises that depart from North America: United States: California: Los Angeles
Cruises that visit Los Angeles
Click on a cruise ship itinerary sailing from Los Angeles (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Los Angeles), please visit: Cruise Search or try our Virtual Cruise Advisor™.
101 Night - Msc World CruiseStarting in Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Feb 6, More...
16 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Feb 9, Sep 20, Dec 28, 2027: Mar 2, Apr 3, More...
6 Night - Cabo & Ensenada CruiseStarting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
16 Night - Hawaiian IslandsStarting in Los Angeles, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 20, More...
54 Night - South Pacific, Australia & New ZealandStarting in Los Angeles, California, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Raiatea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Tauranga, New Zealand, Bay of Islands, New Zealand, Hobart, Australia, Sydney AU, Brisbane, Australia, Noumea, New Caledonia, Mystery Island, Vanuatu, Suva, Fiji, Dravuni Island, Fiji, Apia, Western Samoa, Cross International Date Line, Hilo, Hawaii, Kona, Hawaii, Los Angeles, California
2026 Sails: Mar 13, More...
4 Night - Catalina & Ensenada CruiseStarting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Mar 16, More...
7 Night - Mexican RivieraStarting in Los Angeles, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Mar 28, More...
7 Night - Classic California CoastStarting in Los Angeles, California, San Francisco, California, Santa Barbara, California, San Diego, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Apr 4, More...
Deal link -> Special
25 Night - Los Angeles to SouthamptonStarting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Apr 5, More...
Deal link -> Special
14 Night - Los Angeles to MiamiStarting in Los Angeles, CA, Puerto Quetzal, Guatemala, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Apr 5, More...
