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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager12 Night - Knights & Emperors
Starting in Istanbul, Mytilini (Lesbos), Kusadasi, Heraklion (Crete), Cruising the Ionian Sea, Dubrovnik, Croatia, Kotor, Corfu, Cruising the Ionian Sea, Valletta, Catania (Sicily), Sorrento / Capri, Rome (Civitavecchia)
2026 Sails: Jun 28, More...
Seabourn, Seabourn Quest
Seabourn Quest7 Night - Turkey & Greek Isle Gems
Starting in Istanbul, Turkey, Canakkale, Turkey, Izmir, Turkey, Patmos, Greece, Rhodes, Greece, Spetses, Greece, Piraeus (Athens), Greece
2026 Sails: Jun 28, Oct 18, More...
Viking Ocean, Viking Sea
Viking Sea7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Jun 30, Aug 25, More...
PONANT, Le Boreal
Le Boreal8 Night - Antique Wonders of the Aegean
Starting in Istanbul, Bozcaada, Sailing in the Dardanelles, Patmos, Symi, Amorgos, Sailing in the Santorini Caldera, Paros, Adamas, Milos, Hydra, Athens
2026 Sails: Jul 2, More...
Norwegian Cruise Line, Norwegian Viva
Norwegian Viva9 Night - Greek Isles & Italy
Starting in Istanbul, Turkey, Kusadasi, Turkey, Piraeus / Athens, Greece, Mykonos, Greece, Santorini Island, Greece, Olympia / Katakolon, Greece, Valletta, Malta, Catania, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Jul 13, More...
Azamara Cruises, Azamara Onward
Azamara Onward7 Night - Greece Intensive Cruise : Thessaloniki, Volos & Mykonos
Starting in Istanbul, Canakkale (Kepez), Thessaloniki, Volos, Mykonos, Nafplio, Athens (Piraeus)
2026 Sails: Jul 18, More...
MSC Cruises, MSC Fantasia
MSC Fantasia9 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Katakolon (Olympia), Greece, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Jul 19, Sep 20, More...
Oceania Cruises, Oceania Allura
Oceania Allura7 Night - Legendary Turkey & Greece
Starting in Istanbul, Bozcaada (Troy), Mitilini (Lesbos), Izmir, Chios, Kos, Santorini, Athens (Piraeus)
2026 Sails: Jul 21, More...
Norwegian Line Tours, Norwegian Viva Tours
Norwegian Viva Tours12 Night - Istanbul City Highlights Pre Cruisetour
Starting in At Hotel, Istanbul, Turkey, Kusadasi, Turkey, Santorini Island, Greece, Mykonos, Greece, Piraeus / Athens, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Dubrovnik, Croatia, Montenegro, Split, Croatia, Venice (Ravenna), Italy
2026 Sails: Jul 29, More...
Norwegian Cruise Line, Norwegian Viva
Norwegian Viva10 Night - Greek Isles & Italy
Starting in Istanbul, Turkey, Kusadasi, Turkey, Santorini Island, Greece, Mykonos, Greece, Piraeus / Athens, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Dubrovnik, Croatia, Montenegro, Split, Croatia, Venice (Ravenna), Italy
2026 Sails: Jul 31, More...

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Istanbul Cruise Departures