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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



AmaWaterways Tours, AmaBella Tours
AmaBella Tours20 Night - Grand Danube Cruise with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Grein, Linz, Passau, Villany, Regensburg, Prague
2026 Sails: Jul 24, Aug 21, Nov 13, More...
Norwegian Cruise Line, Norwegian Viva
Norwegian Viva10 Night - Greek Isles & Italy
Starting in Istanbul, Turkey, Kusadasi, Turkey, Santorini Island, Greece, Mykonos, Greece, Piraeus / Athens, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Dubrovnik, Croatia, Montenegro, Split, Croatia, Venice (Ravenna), Italy
2026 Sails: Jul 31, More...
Oceania Cruises, Oceania Regatta
Oceania Regatta17 Night - Mythic Mediterranean
Starting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus), Chania (Crete), Argostoli (Cephalonia), Corfu, Sarande, Bari, Kotor, Dubrovnik, Croatia
2026 Sails: Jul 31, More...
Oceania Cruises, Oceania Regatta
Oceania Regatta10 Night - Hellenic Explorer
Starting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus)
2026 Sails: Jul 31, More...
MSC Cruises, MSC Fantasia
MSC Fantasia9 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Katakolon (Olympia), Greece, Santorini, Greece, Piraeus (Athens), Greece, Istanbul, Turkey
2026 Sails: Aug 15, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Aug 18, More...
MSC Cruises, MSC Fantasia
MSC Fantasia9 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Katakolon (Olympia), Greece, Piraeus (Athens), Greece, Kusadasi, Turkey, Istanbul, Turkey
2026 Sails: Aug 24, More...
Oceania Cruises, Oceania Sirena
Oceania Sirena14 Night - Mediterranean Mosaic
Starting in Istanbul, Izmir, Santorini, Rhodes, Heraklion (Crete), Dubrovnik, Croatia, Kotor, Sarande, Katakolon, Taormina (Sicily), Sorrento / Capri, Rome (Civitavecchia)
2026 Sails: Aug 27, More...
Norwegian Line Tours, Norwegian Viva Tours
Norwegian Viva Tours11 Night - Istanbul City Highlights Pre Cruisetour
Starting in At Hotel, Istanbul, Turkey, Kusadasi, Turkey, Santorini Island, Greece, Mykonos, Greece, Piraeus / Athens, Greece, Olympia / Katakolon, Greece, Valletta, Malta, Catania, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Sep 5, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna5 Night - Mediterranean from Istanbul to Athens (Piraeus)
Starting in Istanbul, Mykonos, Heraklion (Crete), Rhodes, Thira (Santorini), Piraeus (Athens)
2026 Sails: Sep 6, More...

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Istanbul Cruise Departures