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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



AmaWaterways Tours, AmaBella Tours
AmaBella Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Dec 11, 2027: Apr 2, Apr 30, May 28, Jun 25, Jul 23, Aug 20, Sep 17, Oct 15, Nov 12, 2028: Mar 3, Mar 31, Apr 28, May 26, Jun 23, Jul 21, Aug 18, Sep 15, Oct 13, More...
Viking Ocean, Viking Neptune
Viking Neptune7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Dec 22, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Kusadasi, Turkey, Istanbul, Turkey
2026 Sails: Dec 30, 2027: Mar 17, Mar 24, Mar 31, Apr 7, Apr 14, Oct 27, Nov 3, Nov 10, Nov 17, Nov 24, Dec 1, Dec 8, Dec 15, Dec 22, Dec 29, 2028: Jan 5, Jan 12, Jan 19, Jan 26, Feb 2, Feb 9, Feb 16, Feb 23, More...
MSC Orchestra3 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy
2027 Sails: Jan 6, Apr 21, 2028: Mar 29, More...
MSC Lirica7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Kusadasi, Turkey, Istanbul, Turkey
2027 Sails: Jan 13, Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, More...
Viking Ocean, Viking Mira
Viking Mira7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2027 Sails: Jan 13, 2028: Jan 5, More...
Viking Ocean, Viking Mira
Viking Mira14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2027 Sails: Jan 13, More...
Regent Seven Seas, Seven Seas Navigator
Seven Seas Navigator14 Night - Pharaohs & Empires
Starting in Istanbul, Canakkale (Troy), Kusadasi, Cruising the Aegean Sea, Rhodes, Alanya, Limassol, Cruising the Mediterranean Sea, Alexandria EG, Cruising the Mediterranean Sea, Heraklion (Crete), Athens (Piraeus)
2027 Sails: Jan 15, More...
MSC Cruises, MSC Lirica
MSC Lirica3 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy
2027 Sails: Mar 10, More...
Viking Ocean, Viking Mira
Viking Mira14 Night - Ancient Adriatic Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice
2027 Sails: Mar 10, More...

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Istanbul Cruise Departures