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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Viking Ocean, Viking Astrea
Viking Astrea7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2027 Sails: Oct 31, More...
Viking Ocean, Viking Astrea
Viking Astrea21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Oct 31, More...
MSC Cruises, MSC Splendida
MSC Splendida4 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy
2027 Sails: Nov 2, More...
Regent Seven Seas, Seven Seas Splendor
Seven Seas Splendor11 Night - Cinematic Shores
Starting in Istanbul, Canakkale (Troy), Kusadasi, Athens (Piraeus), Cruising the Ionian Sea, Messina (Sicily), Naples / Pompeii, Rome (Civitavecchia), Tuscany (Livorno), Toulon, Palamos, Barcelona
2027 Sails: Nov 9, More...
Explora Journeys, EXPLORA V
EXPLORA V7 Night - A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders
Starting in Istanbul, Canakkale, Kusadasi, Heraklion, Crete, Siracusa (Sicily), Port of Naples, Civitavecchia (Rome)
2027 Sails: Dec 12, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2027 Sails: Dec 29, More...
Viking Ocean, Viking Mira
Viking Mira14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Heraklion), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Jan 5, More...
Viking Ocean, Viking Mira
Viking Mira21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Heraklion), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2028 Sails: Jan 5, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2028 Sails: Jan 12, More...
Viking Ocean, Viking Vela
Viking Vela14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Jan 25, More...

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Istanbul Cruise Departures