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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



MSC Cruises, MSC Seaview
MSC Seaview7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Split, Croatia, Piraeus (Athens), Greece
2028 Sails: Oct 26, More...
Azamara Cruises, Azamara Journey
Azamara Journey7 Night - Greece Intensive Cruise : Chios, Rhodes & Santorini
Starting in Istanbul, Canakkale (Kepez), Chios, Rhodes, Agios Nikolaos, (Crete), Santorini, Mykonos, Athens (Piraeus)
2028 Sails: Oct 28, More...
Viking Ocean, Viking Libra
Viking Libra14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Nov 1, 2029: Jan 24, More...
Viking Ocean, Viking Libra
Viking Libra7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Nov 1, 2029: Jan 24, More...
Viking Ocean, Viking Astrea
Viking Astrea7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Nov 15, Dec 27, More...
Viking Ocean, Viking Astrea
Viking Astrea14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Nov 15, Dec 27, More...
Oceania Cruises, Oceania Allura
Oceania Allura9 Night - Aegean & Holy Land
Starting in Istanbul, Rhodes, Antalya, Limassol, Jerusalem (Haifa), Heraklion (Crete), Athens (Piraeus)
2028 Sails: Nov 25, More...
Holland America, Rotterdam
Rotterdam21 Night - Mediterranean Crossing : Greek Isles, Italy & Spain
Starting in Istanbul, Turkey, Mykonos, Greece, Souda (Chania), Greece, Messina, Italy, Cruising Strait of Messina, Evening cruising Stromboli Volcano, Naples (Pompeii / Amalfi), Italy, Civitavecchia (Rome), Italy, Livorno (Florence / Pisa), Italy, Cartagena ES, Gibraltar, Fort Lauderdale, Florida
2028 Sails: Dec 2, More...
Holland America, Rotterdam
Rotterdam7 Night - Mediterranean Splendor : Greek Isles, Sicily & Naples
Starting in Istanbul, Turkey, Mykonos, Greece, Souda (Chania), Greece, Messina, Italy, Cruising Strait of Messina, Evening cruising Stromboli Volcano, Naples (Pompeii / Amalfi), Italy, Civitavecchia (Rome), Italy
2028 Sails: Dec 2, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager14 Night - Season of Wonder
Starting in Istanbul, Cruising the Aegean Sea, Izmir, Bodrum, Cruising the Mediterranean Sea, Jerusalem (Haifa), Cruising the Mediterranean Sea, Alexandria EG, Cruising the Mediterranean Sea, Katakolon, Chania (Crete), Athens (Piraeus)
2028 Sails: Dec 14, More...

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Istanbul Cruise Departures