Istanbul Cruise Departures
Cruises that depart from Mediterranean: Turkey: Istanbul
Cruises that visit Istanbul
See all River Cruises that depart from Istanbul
14 Night - Hidden Gems of Turkey, Greece, Malta, Italy & Spain
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Rhodes, Greece, Santorini, Greece, Piraeus (Athens), Greece, Valletta, Malta, Trapani, Italy, Cagliari, Sardinia, Italy, Alghero, Italy, Mahon, Menorca, Spain, Barcelona, Spain
2027 Sails: Oct 23, More...22 Night - Mediterranean Mosaic : Turkey, Greece, Italy & Spain
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Rhodes, Greece, Santorini, Greece, Piraeus (Athens), Greece, Valletta, Malta, Trapani, Italy, Cagliari, Sardinia, Italy, Alghero, Italy, Mahon, Menorca, Spain, Barcelona, Spain, Valencia, Spain, Cartagena ES, Motril (Granada), Spain, Melilla, Spanish Morocco, Spain, Cadiz (Seville), Spain, Leixoes (Porto), Portugal, Lisbon, Portugal
2027 Sails: Oct 23, More...
21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2027 Sails: Oct 23, More...14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2027 Sails: Oct 23, More...7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2027 Sails: Oct 23, More...
11 Night - Mediterranean with Greek Isles & Italy
Starting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Chania), Greece, Valletta, Malta, Sicily (Messina), Italy, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2027 Sails: Oct 26, More...
10 Night - Ancient Indulgence
Starting in Istanbul, Bozcaada (Troy), Thessaloniki, Milos, Katakolon, Kotor, Dubrovnik, Croatia, Split, Koper, Trieste
2027 Sails: Oct 28, More...
7 Night - Greek Isles & Turkey Cruise
Starting in Istanbul, Turkey, Ephesus (Kusadasi), Turkey, Bodrum, Turkey, Rhodes, Greece, Santorini, Greece, Chania (Souda), Crete, Greece, Athens (Piraeus), Greece
2027 Sails: Oct 29, More...
5 Night - Cruise from Istanbul to Athens (Piraeus)
Starting in Istanbul, Izmir, Volos, Santorini, Nafplion, Athens (Piraeus)
2027 Sails: Oct 31, More...
14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2027 Sails: Oct 31, More...
Cruises that depart from Mediterranean: Turkey: Istanbul
Cruises that visit Istanbul
See all River Cruises that depart from Istanbul
Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Hidden Gems of Turkey, Greece, Malta, Italy & SpainStarting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Rhodes, Greece, Santorini, Greece, Piraeus (Athens), Greece, Valletta, Malta, Trapani, Italy, Cagliari, Sardinia, Italy, Alghero, Italy, Mahon, Menorca, Spain, Barcelona, Spain
2027 Sails: Oct 23, More...
22 Night - Mediterranean Mosaic : Turkey, Greece, Italy & SpainStarting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Rhodes, Greece, Santorini, Greece, Piraeus (Athens), Greece, Valletta, Malta, Trapani, Italy, Cagliari, Sardinia, Italy, Alghero, Italy, Mahon, Menorca, Spain, Barcelona, Spain, Valencia, Spain, Cartagena ES, Motril (Granada), Spain, Melilla, Spanish Morocco, Spain, Cadiz (Seville), Spain, Leixoes (Porto), Portugal, Lisbon, Portugal
2027 Sails: Oct 23, More...
21 Night - Iconic Mediterranean TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2027 Sails: Oct 23, More...
14 Night - Ancient Mediterranean AntiquitiesStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2027 Sails: Oct 23, More...
7 Night - Ancient Mediterranean TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2027 Sails: Oct 23, More...
11 Night - Mediterranean with Greek Isles & ItalyStarting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Chania), Greece, Valletta, Malta, Sicily (Messina), Italy, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2027 Sails: Oct 26, More...
10 Night - Ancient IndulgenceStarting in Istanbul, Bozcaada (Troy), Thessaloniki, Milos, Katakolon, Kotor, Dubrovnik, Croatia, Split, Koper, Trieste
2027 Sails: Oct 28, More...
7 Night - Greek Isles & Turkey CruiseStarting in Istanbul, Turkey, Ephesus (Kusadasi), Turkey, Bodrum, Turkey, Rhodes, Greece, Santorini, Greece, Chania (Souda), Crete, Greece, Athens (Piraeus), Greece
2027 Sails: Oct 29, More...
5 Night - Cruise from Istanbul to Athens (Piraeus)Starting in Istanbul, Izmir, Volos, Santorini, Nafplion, Athens (Piraeus)
2027 Sails: Oct 31, More...
14 Night - Ancient Mediterranean AntiquitiesStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2027 Sails: Oct 31, More...
