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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



AmaWaterways Tours, AmaBella Tours
AmaBella Tours20 Night - Grand Danube (Taste of Christmas) with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Grein, Linz, Passau, Villany, Regensburg, Prague
2026 Sails: Nov 13, More...
AmaWaterways Tours, AmaBella Tours
AmaBella Tours12 Night - Gems of Southeast Europe (Taste of Christmas) with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Novi Sad, Mohacs, Budapest, Vienna
2026 Sails: Nov 13, More...
Viking Ocean, Viking Star
Viking Star7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Nov 14, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Nov 18, Nov 25, Dec 2, Dec 9, Dec 16, Dec 23, More...
AmaWaterways Tours, AmaMagna Tours
AmaMagna Tours20 Night - Grand Danube (Taste of Christmas) with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Ilok, Mohacs, Budapest, Bratislava, Vienna, Spitz, Linz, Passau, Villany, Regensburg, Prague
2026 Sails: Nov 19, More...
Viking Ocean, Viking Saturn
Viking Saturn7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Nov 21, More...
AmaWaterways Tours, AmaVerde Tours
AmaVerde Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Golubac, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Nov 27, 2027: Mar 19, Apr 16, May 14, Jun 11, Jul 9, Aug 6, Sep 3, Oct 1, Oct 29, 2028: Mar 17, Apr 14, May 12, Jun 9, Jul 7, Aug 4, Sep 1, Oct 27, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager10 Night - Turkish Treasures
Starting in Istanbul, Cruising the Aegean Sea, Izmir, Cruising the Aegean Sea, Marmaris, Limassol, Rhodes, Heraklion (Crete), Nafplion, Athens (Piraeus)
2026 Sails: Nov 27, More...
Viking Ocean, Viking Vesta
Viking Vesta14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Dec 9, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Dec 9, 2027: Jan 20, More...

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Istanbul Cruise Departures