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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



AmaWaterways Tours, AmaBella Tours
AmaBella Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Apr 3, May 1, May 29, Jun 26, Jul 24, Aug 21, Sep 18, Oct 16, Dec 11, 2027: Apr 2, Apr 30, May 28, Jun 25, Jul 23, Aug 20, Sep 17, Oct 15, Nov 12, More...
AmaWaterways Tours, AmaBella Tours
AmaBella Tours20 Night - Grand Danube Cruise with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Prudhoe Bay / Deadhorse, Grein, Linz, Passau, Vilshofen, Regensburg, Prague
2026 Sails: Apr 3, May 29, Jun 26, Jul 24, Aug 21, Nov 13, More...
Viking Ocean, Viking Mars
Viking Mars7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Apr 6, 2027: May 1, 2028: Apr 4, More...
Windstar, Star Legend
Star Legend8 Night - Aegean Sea Odyssey via the Corinth Canal
Starting in Istanbul, Myrina (Lemnos), Mykonos, Kusadasi, Bodrum, Santorini, Delphi, Corinth Canal, Athens, Greece
2026 Sails: Apr 16, May 2, Oct 19, More...
AmaWaterways Tours, AmaVerde Tours
AmaVerde Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Apr 17, May 15, Jun 12, Jul 10, Aug 7, Sep 4, Oct 2, Nov 27, 2027: Mar 19, Apr 16, May 14, Jun 11, Jul 9, Aug 6, Sep 3, Oct 1, Oct 29, More...
AmaWaterways Tours, AmaVerde Tours
AmaVerde Tours20 Night - Grand Danube Cruise with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Prudhoe Bay / Deadhorse, Grein, Linz, Passau, Vilshofen, Regensburg, Prague
2026 Sails: Apr 17, May 15, Jun 12, Jul 10, Aug 7, Oct 2, Oct 30, More...
Viking Ocean, Viking Saturn
Viking Saturn7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Apr 18, More...
Explora Journeys, EXPLORA I
EXPLORA I4 Night - A Journey Through Enduring Culture & Island Grace
Starting in Istanbul, Cesme, Syros (Syra), Piraeus (Athens)
2026 Sails: Apr 20, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn11 Night - Istanbul & Enchantment of Eastern Europe
Starting in Istanbul, Istanbul / Bucharest, Bucharest / Giurgiu, Rousse, Vidin, Donji Milanovac / Golubac, Belgrade, Vukovar, Ordas, Budapest
2026 Sails: Apr 21, More...
Viking Ocean, Viking Jupiter
Viking Jupiter7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Apr 22, 2028: Aug 19, More...

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Istanbul Cruise Departures