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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



MSC Cruises, MSC Lirica
MSC Lirica Cruise Ship7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2025 Sails: Dec 31, More...
MSC Cruises, MSC Lirica
MSC Lirica Cruise Ship7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Jan 7, Jan 28, Feb 11, Feb 18, Feb 25, Mar 11, More...
MSC Cruises, MSC Lirica
MSC Lirica Cruise Ship7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Jan 14, Jan 21, Mar 4, More...
AmaWaterways Cruise Tours, AmaVerde Cruise Tours
AmaVerde Cruise Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Iron Gates, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Mar 20, Apr 17, May 15, Jun 12, Jul 10, Aug 7, Sep 4, Nov 27, 2027: Mar 19, Apr 16, May 14, Jun 11, Jul 9, Aug 6, Sep 3, Oct 1, Oct 29, More...
MSC Cruises, MSC Lirica
MSC Lirica Cruise Ship3 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy
2026 Sails: Mar 25, More...
AmaWaterways Cruise Tours, AmaBella Cruise Tours
AmaBella Cruise Tours20 Night - Grand Danube Cruise with Istanbul Pre-Cruise and Prague Post-Cruise
Starting in Istanbul, Bucharest, Giurgiu, Rousse, Vidin, Iron Gates, Belgrade, Vukovar, Mohacs, Budapest, Bratislava, Vienna, Weissenkirchen, Scenic Cruising, Grein, Linz, Passau, Vilshofen, Regensburg, Prague
2026 Sails: Apr 3, May 29, Jul 24, Aug 21, More...
AmaWaterways Cruise Tours, AmaBella Cruise Tours
AmaBella Cruise Tours12 Night - Gems of Southeast Europe with Istanbul Pre-Cruise and Vienna Post-Cruise
Starting in Istanbul, Giurgiu, Rousse, Vidin, Iron Gates, Belgrade, Vukovar, Mohacs, Budapest, Vienna
2026 Sails: Apr 3, May 1, May 29, Jun 26, Jul 24, Aug 21, Sep 18, Oct 16, Dec 11, 2027: Apr 2, Apr 30, May 28, Jun 25, Jul 23, Aug 20, Sep 17, Oct 15, Nov 12, More...
Viking Ocean, Viking Mars
Viking Mars Cruises7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Apr 6, 2027: May 1, 2028: Apr 4, More...
Viking Ocean, Viking Mars
Viking Mars Cruises21 Night - Adriatic & Mediterranean Sojourn
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Apr 6, More...
Viking Ocean, Viking Mars
Viking Mars Cruises14 Night - Ancient Adriatic Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Fusina)
2026 Sails: Apr 6, More...

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Istanbul Cruise Departures