Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Carnival Cruise Lines, Carnival Miracle

16 Night - Journeys - Panama Canal
Starting in Tampa, Fl, Grand Cayman, Cayman Islands, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 11, More...

Celebrity Cruises, Celebrity Apex

7 Night - St. Kitts, San Juan & Puerto Plata
Starting in Orlando (Port Canaveral), Fl, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Basseterre, St Kitts and Nevis, Orlando (Port Canaveral), Fl
2026 Sails: Apr 11, More...

Celebrity Cruises, Celebrity Eclipse

8 Night - Antigua, St. Kitts, & San Juan
Starting in Fort Lauderdale, Florida, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Fort Lauderdale, Florida
2026 Sails: Apr 11, More...

Disney Cruise Line, Disney Destiny

Deal link -> Special

5 Night - Western Caribbean Cruise from Fort Lauderdale
Starting in Port Everglades, Cozumel, Mexico, Castaway Cay, Port Everglades
2026 Sails: Apr 11, Apr 25, May 9, May 23, More...

Disney Cruise Line, Disney Treasure

7 Night - Eastern Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Tortola, St Thomas, US Virgin Islands, Castaway Cay, Port Canaveral
2026 Sails: Apr 11, May 9, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, 2027: Jan 30, Feb 13, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Apr 11, More...

MSC Cruises, MSC Grandiosa

21 Night - Msc Grand Voyages
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida, Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal, Barcelona, Spain
2026 Sails: Apr 11, More...

MSC Cruises, MSC World America

7 Night - Caribbean and Antilles
Starting in Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 18, Aug 1, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2027: Jan 2, Jan 16, Jan 30, Feb 13, Mar 13, More...

Norwegian Cruise Line, Norwegian Encore

18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca
2026 Sails: Apr 11, More...

Norwegian Cruise Line, Norwegian Encore

22 Night - Repo - Panama Canal
Starting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Astoria, Or, Victoria CA, Canada, Seattle, Wa
2026 Sails: Apr 11, More...

<= Back

More =>