Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Casa de Campo : La Romana : Punta Cana : Santo Domingo

7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Fort-de-France, Martinique, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Apr 19, May 3, May 17, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, More...

MSC Cruises, MSC Opera

14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic
2027 Sails: Nov 15, Dec 13, 2028: Jan 10, Jan 24, Feb 7, Feb 21, Mar 6, Mar 20, More...

MSC Cruises, MSC Opera

7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint Georges, Grenada, La Romana, Dominican Republic
2027 Sails: Nov 22, 2028: Jan 31, More...

MSC Cruises, MSC Opera

14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Nov 22, Dec 6, 2028: Feb 14, Feb 28, Mar 13, Mar 27, More...

MSC Cruises, MSC Opera

14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, Sao Cristovao, Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Dec 20, 2028: Jan 3, More...

MSC Cruises, MSC Opera

14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint Georges, Grenada, La Romana, Dominican Republic
2027 Sails: Dec 27, More...

MSC Cruises, MSC Opera

7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint Georges, Granada, La Romana, Dominican Republic
2028 Sails: Jan 17, More...

MSC Cruises, MSC Opera

14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Saint Georges, Granada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2028 Sails: Jan 31, More...

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Dominican Republic Cruise Departures