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Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: La Romana : Punta Cana : Santo Domingo


MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic
2027 Sails: Nov 15, Nov 29, Dec 13, More...
MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint Georges, Granada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Nov 22, More...
MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Dec 6, Dec 20, More...
MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint Georges, Grenada, La Romana, Dominican Republic
2028 Sails: Feb 14, More...
MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, Saint Martin, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2028 Sails: Feb 21, More...

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Dominican Republic Cruise Departures