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Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: La Romana : Santo Domingo


MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Fort-de-France, Martinique, St Johns AG, Antigua, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Bridgetown, Barbados, Fort-de-France, Martinique, Pointe-A-Pitre, Guadeloupe, Road Town (Tortola), British Virgin Islands, La Romana, Dominican Republic
2027 Sails: May 3, Jun 14, Jul 26, Aug 9, Aug 23, Sep 6, Nov 1, More...
MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Bridgetown, Barbados, Fort-de-France, Martinique, Pointe-A-Pitre, Guadeloupe, Road Town (Tortola), British Virgin Islands, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Fort-de-France, Martinique, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Jun 7, More...
MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic
2027 Sails: Nov 15, Nov 29, Dec 13, More...
MSC Cruises, MSC Opera
MSC Opera14 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint George, Grenada, La Romana, Dominican Republic, Catalina Island, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, St Johns AG, Antigua, La Romana, Dominican Republic
2027 Sails: Nov 22, Dec 6, Dec 20, More...
MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint Georges, Grenada, La Romana, Dominican Republic
2027 Sails: Nov 22, More...
MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Kralendijk, Bonaire, Saint Georges, Granada, La Romana, Dominican Republic
2028 Sails: Jan 3, More...
PONANT, Le Champlain
Le Champlain7 Night - Secret Treasures of the Lesser Antilles
Starting in La Romana, Punta Cana, Virgin Gorda, Little Bay, Deshaies, Roseau, Speightstown, Fort-de-France
2028 Sails: Feb 9, More...

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Dominican Republic Cruise Departures