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Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Casa de Campo : La Romana : Punta Cana : Santo Domingo


Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises18 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre, St Lucia Castries, Bridgetown, Barbados, Santa Cruz de Tenerife, Tangier, Barcelona, Marseille
2026 Sails: Mar 9, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises17 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre, St Lucia Castries, Bridgetown, Barbados, Santa Cruz de Tenerife, Tangier, Barcelona
2026 Sails: Mar 9, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica Cruise Ship13 Night - Transatlantic from Casa De Campo / La Romana
Starting in Casa De Campo / La Romana, St Maarten (Philipsburg), Santa Cruz de Tenerife, Cadice, Barcelona
2026 Sails: Mar 15, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica Cruise Ship15 Night - Caribbean from La Romana to Savona
Starting in Casa De Campo / La Romana, St Maarten (Philipsburg), Santa Cruz de Tenerife, Cadice, Barcelona, Marseille, Savona
2026 Sails: Mar 15, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica Cruise Ship14 Night - Transatlantic from Casa De Campo / La Romana
Starting in Casa de Campo, Dominican Republic, St Maarten (Antilles), Santa Cruz de Tenerife, Cadiz, Spain, Barcelona, Spain, Marseille, France
2026 Sails: Mar 15, More...
Norwegian Cruise Line (NCL), NCL Norwegian Sky
NCL Norwegian Sky Cruise Ship13 Night - Repo - Transatlantic
Starting in Punta Cana (La Romana), Dominican Republic, Tortola, British Virgin Islands, Ponta Delgada, Portugal, Lisbon, Portugal, Vigo, Spain, La Coruna, Spain, Le Havre / Paris, France
2026 Sails: Apr 6, More...
MSC Cruises, MSC Opera
MSC Opera Cruise Ship3 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Bridgetown, Barbados
2026 Sails: Nov 16, 2027: Apr 12, More...
MSC Cruises, MSC Opera
MSC Opera Cruise Ship7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Bridgetown, Barbados, Fort-de-France, Martinique, Pointe-A-Pitre, Guadeloupe, Road Town (Tortola), British Virgin Islands, La Romana, Dominican Republic
2026 Sails: Nov 16, Nov 30, Dec 14, 2027: Feb 8, Apr 12, Apr 26, May 10, May 24, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, More...
MSC Cruises, MSC Opera
MSC Opera Cruise Ship7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Samana Bay, Dominican Republic, Virgin Gorda, British Virgin Islands, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Catalina Island, Dominican Republic, La Romana, Dominican Republic
2026 Sails: Nov 23, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa Cruise Ship7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Dominican Republic, Guadeloupe (Antilles), Martinique (Antilles), St Kitts (Antilles), Antigua (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic
2026 Sails: Nov 30, More...

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Dominican Republic Cruise Departures