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Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Casa de Campo : La Romana : Punta Cana : Santo Domingo


MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Samana Bay, Dominican Republic, Virgin Gorda, British Virgin Islands, Basseterre, St Kitts and Nevis, Philipsburg, St Maarten, Catalina Island, Dominican Republic, La Romana, Dominican Republic
2026 Sails: Dec 21, 2027: Jan 4, Jan 18, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa14 Night - Western Caribbean from Casa De Campo / La Romana
Starting in La Romana, Catalina Island, Cabo Rojo, Puerto Plata, Dominican Republic, Grand Turk, Arroyo Barril (Samana), La Romana, Castries, St Lucia, Bridgetown, Barbados, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), La Romana
2026 Sails: Dec 27, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa7 Night - Caribbean Roundtrip from La Romana
Starting in La Romana, Catalina Island, Cabo Rojo, Puerto Plata, Dominican Republic, Grand Turk, Arroyo Barril (Samana), La Romana
2026 Sails: Dec 27, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Dominican Republic, Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Lucia (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic
2026 Sails: Dec 28, More...
MSC Cruises, MSC Opera
MSC Opera7 Night - South Caribbean
Starting in La Romana, Dominican Republic, Catalina Island, Dominican Republic, Bridgetown, Barbados, Fort-de-France, Martinique, St Johns AG, Antigua, Road Town (Tortola), British Virgin Islands, La Romana, Dominican Republic
2026 Sails: Dec 28, 2027: Jan 25, Feb 22, Mar 8, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa7 Night - Western Caribbean from Casa De Campo / La Romana
Starting in La Romana, Castries, St Lucia, Bridgetown, Barbados, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), La Romana
2027 Sails: Jan 3, Jan 31, Feb 14, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa14 Night - Caribbean Roundtrip from La Romana
Starting in La Romana, Castries, St Lucia, Bridgetown, Barbados, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), La Romana, Catalina Island, Arroyo Barril (Samana), Grand Turk, Amber Cove, Cabo Rojo, La Romana
2027 Sails: Jan 3, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic
2027 Sails: Jan 4, Feb 8, Feb 15, Feb 22, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa7 Night - Caribbean Roundtrip from La Romana
Starting in La Romana, Catalina Island, Arroyo Barril (Samana), Grand Turk, Amber Cove, Cabo Rojo, La Romana
2027 Sails: Jan 10, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa14 Night - Caribbean Roundtrip from La Romana
Starting in La Romana, Catalina Island, Arroyo Barril (Samana), Grand Turk, Amber Cove, Cabo Rojo, La Romana, Fort-de-France, Bridgetown, Barbados, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), La Romana
2027 Sails: Jan 10, More...

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Dominican Republic Cruise Departures