Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Plitvice Lakes : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Tagus River : Vltava River : Volkach River : Water of Leith River

Amadeus River, MS Amadeus Cara

14 Night - Across Europe - Amsterdam to Budapest
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Emmersdorf, Vienna, Bratislava, Budapest
2026 Sails: May 28, More...

AmaWaterways Tours, AmaStella Tours

16 Night - Magnificent Europe (Smithsonian Journeys) with Amsterdam Pre-Cruise
Starting in Amsterdam, Cologne, Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 28, More...

Uniworld Tours, River Duchess Tours

23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: May 29, Aug 21, More...

AmaWaterways, AmaStella

14 Night - Magnificent Europe (Smithsonian Journeys)
Starting in Amsterdam, Cologne, Rudesheim, Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 30, More...

Avalon Waterways, Avalon Illumination

14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: May 30, Aug 1, Sep 26, 2027: Jun 29, Aug 22, More...

Emerald Cruises, Emerald Dawn

14 Night - Splendours of Europe
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: May 30, Aug 8, Sep 5, Oct 17, More...

Emerald Cruises, Emerald Dawn

17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: May 30, Aug 8, More...

Emerald Cruises, Emerald Sun

14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: May 30, 2027: May 7, Jun 4, Oct 18, Nov 15, More...

Avalon Waterways, Avalon Impression

14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 2, Aug 4, Sep 29, 2027: May 28, Jul 21, Sep 13, More...

Avalon Waterways Tours, Avalon Vista Tours

17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 3, Jun 17, Jul 1, Jul 15, Aug 26, Sep 9, More...

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