Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

7 Night - Rhine & Danube Symphony
Starting in Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau
2026 Sails: Aug 18, More...

Scenic Luxury, Scenic Jasper

17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Aug 18, More...

Viking River, Viking Gymir

14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: Aug 19, Nov 11, 2027: Apr 26, May 24, Jun 21, Jul 19, Aug 16, Sep 13, Oct 11, Nov 8, 2028: May 22, Jun 19, Jul 17, Aug 14, Sep 11, Oct 9, Nov 6, More...

Uniworld Tours, River Duchess Tours

23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: Aug 21, More...

AmaWaterways Tours, AmaCerto Tours

13 Night - Europe's Rivers & Castles with Paris Pre-Cruise and Prague Post-Cruise
Starting in Paris, Luxembourg, Bernkastel, Cochem, Koblenz Am Rhein, Wertheim, Wurzburg, Eltmann, Nuremberg, Prague
2026 Sails: Aug 23, Oct 18, More...

Scenic Luxury, Scenic Amber

14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Aug 24, More...

Scenic Luxury, Scenic Amber

Emerald Cruises, Emerald Astra

10 Night - The Majestic Rhine & Berlin
Starting in Zurich / Basel (Huningue), Breisach / Colmar, Strasbourg, Rastatt (Baden-Baden), Mannheim (Heidelberg), Koblenz, Rudesheim, Mainz / Frankfurt / Berlin, Berlin
2026 Sails: Aug 25, More...

Emerald Cruises, Emerald Astra

10 Night - The Majestic Rhine & Berlin
Starting in Basel (Huningue), Breisach / Colmar, Strasbourg, Rastatt (Baden-Baden), Mannheim (Heidelberg), Koblenz, Rudesheim, Mainz / Frankfurt / Berlin, Berlin
2026 Sails: Aug 25, More...

Viking River, Viking Ve

14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Aug 25, 2028: May 30, Jun 27, Jul 25, Aug 22, Sep 19, Oct 17, More...

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